Results 171 to 180 of about 224,518 (341)

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

A multi‐trait evaluation of patterns and fitness consequences of breeding phenology plasticity with nocturnal warming and food restriction in a lizard

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Faced with climate warming, ectothermic species shift their breeding phenology, which is in part attributed to an acceleration of gestation or incubation in warmer environments.
Théo Bodineau, Pierre de Villemereuil, Baptiste Lemaire, Simon Agostini, Beatriz Decencière, Matéo Millet, Sandrine Meylan, Jean‐François Le Galliard   +7 more
wiley   +1 more source

Isolation and initial characterization of microvascular endothelial cells derived from the retoorbital connective tissue of patients with Graves ophthalmopathy [PDF]

, 1994
Bahn, R. S., Heufelder, A. E., Scriba, Peter Christian   +2 more
core   +1 more source

Genital Herpes Zoster in an Immunocompetent Adult: A Rare Presentation

JEADV Clinical Practice, EarlyView.
Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Aditi Joshi, Prakriti Lamichhane   +4 more
wiley   +1 more source

Living Low and Dry: Costs of and Resilience to Soil Hydric Stress in a Fossorial Amphisbaenian Reptile

Integrative Zoology, EarlyView.
Soil drought imposes moderate, temporary costs on a strictly fossorial amphisbaenian reptile. However, these animals seem to cope with, at least, moderately short droughts thanks to their peculiar adaptations to living in an underground environment. ABSTRACT The physiological traits of animals can be strongly influenced by climatic fluctuations, and ...
José Martín, Álvaro Navarro‐Castilla, Alejandro de la Concha, José Javier Cuervo, Isabel Barja, Pilar López   +5 more
wiley   +1 more source

An update on bacterial brain abscess in immunocompetent patients.

Clinical Microbiology and Infection, 2017
R. Sonneville, R. Ruimy, N. Benzonana, L. Riffaud, A. Carsin, J. Tadié, C. Piau, M. Revest, P. Tattevin   +8 more
semanticscholar   +1 more source

A Dermal Plaque on the Arm

JEADV Clinical Practice, EarlyView.
Claudine Howard‐James, Aisling Nolan, Graham Woods, Ian McDonald   +3 more
wiley   +1 more source

Patterns of Surgical Prophylaxis Prescribing for Dentoalveolar Procedures in Australian Hospitals: 2016–2022

Australian Dental Journal, EarlyView.
ABSTRACT Background Antimicrobials are an adjunctive therapy in clinical dentistry. In dentoalveolar surgery, antimicrobials are not routinely required for surgical prophylaxis. This retrospective analysis of the Australian Surgical National Antimicrobial Prescribing Survey (Surgical NAPS) dataset aimed to evaluate the guideline compliance and ...
Jane Chen, Marietta Taylor, Rodney James, Karin Thursky, Michael McCullough, Leanne Teoh, Courtney Ierano   +6 more
wiley   +1 more source

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

Allergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang, Telly Sepahpour, Stephanie Kortchak, Kirthiram Krishnaveni Sivakumar, Spyros Karaiskos, Ngoc Pham, Yura Jang, Montserrat Puig, Michael Norcross   +8 more
wiley   +1 more source

Three‐dimensional patient‐derived endometriosis model for drug evaluation

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Yuqi Li, Wei Shao, Xiaoxiao Gao, Yongxing Wang, Jinzhi Li, Liansuo Zhang, Yanyan Xing, Wentao Su, Yan Cheng, Li Wang, Songping Liu   +10 more
wiley   +1 more source