Results 31 to 40 of about 224,518 (341)

Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone [PDF]

, 1975
The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by
Baltimore, David, Kung, Patrick C., McCaffrey, Ronald P., Silverstone, Allen E.   +3 more
core   +1 more source

3D Immunocompetent Organ-on-a-Chip Models.

Small Methods, 2020
In recent years, engineering of various human tissues in microphysiologically relevant platforms, known as organs-on-chips (OOCs), has been explored to establish in vitro tissue models that recapitulate the microenvironments found in native organs and ...
S. Maharjan, Berivan Çeçen, Y. S. Zhang   +2 more
semanticscholar   +1 more source

Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. [PDF]

, 2001
Long-term expression of coagulation factor IX (FIX) has been observed in murine and canine models following administration of recombinant adeno-associated viral (rAAV) vectors into either the portal vein or muscle. These studies were designed to evaluate
Davidoff, A, Hanawa, H, Nathwani, AC, Nienhuis, AW, Vanin, EF, Zhou, JF   +5 more
core   +1 more source

Fatal tuberculous brain abscesses in an immunocompetent woman

The Pan African Medical Journal, 2015
The identification of the cause of acute encephalitis is difficult in spite of many developed diagnosis strategies. The cause is unknown in nearly 30 to 40 % of cases. Tuberculosis is endemic in Tunisia.
Hassen Ben Ghezala, Salah Snouda
doaj   +1 more source

Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity. [PDF]

, 2017
BackgroundProdrug-activator gene therapy with Toca 511, a tumor-selective retroviral replicating vector (RRV) encoding yeast cytosine deaminase, is being evaluated in recurrent high-grade glioma patients.
Gruber, Harry E, Hacke, Katrin, Hiraoka, Kei, Huang, Tiffany T, Inagaki, Akihito, Jolly, Douglas J, Kamijima, Shuichi, Kasahara, Noriyuki, Kato, Yuki, Kruse, Carol A, Matsumoto, Hiroshi, Mitchell, Leah A, Ostertag, Derek, Robbins, Joan M, Takahashi, Masamichi   +14 more
core   +1 more source

Non-typhoidal Salmonella myocarditis in an immunocompetent young adult with diarrhea

The Pan African Medical Journal, 2019
Myocarditis is the inflammation of the heart muscle and it is caused by a wide range of infectious and non-infectious conditions. Non-typhoidal Salmonella infection, a common foodborne illness worldwide, only rarely causes myocarditis. We describe a case
Lamprini Markaki, Nikolaos Spernovasilis, Dimitris Lempidakis, Evangelos Kokorakis, Ioannis Gialamas, Stylianos Petousis, Diamantis Kofteridis, Emmanuel Simantirakis   +7 more
doaj   +1 more source

Pulmonary Cryptococcosis: comparison of Cryptococcal antigen detection and radiography in Immunocompetent and Immunocompromised patients

BMC Infectious Diseases, 2020
Background We compared the cryptococcal antigen detection and imaging findings between immunocompetent and immunocompromised patients in whom pulmonary cryptococcosis had been diagnosed.
jingqi Min, Kunlun Huang, Chanmei Shi, Laifu Li, Fuye Li, T. Zhu, H. Deng   +6 more
semanticscholar   +1 more source

Morphine activates neuroinflammation in a manner parallel to endotoxin [PDF]

, 2012
Opioids create a neuroinflammatory response within the CNS, compromising opioid-induced analgesia and contributing to various unwanted actions. How this occurs is unknown but has been assumed to be via classic opioid receptors.
A. A. Somogyi, A. J. de Jesus, A. Reddy, Barochia, Bevan, Bokhari, Dziarski, H. Yin, Hargreaves, Hoshino, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, J. Thomas, Jacquet, Joce, K. Cheng, K. Ramos, Kirikae, L. C. Loram, L. R. Watkins, Lewis, Li, Liu, Liu, M. R. Hutchinson, Manavalan, Milligan, Nagyoszi, Narita, Ohto, Park, Resman, Rice, Slivka, Takeuchi, Viriyakosol, Watkins, X. Wang, Youn   +42 more
core   +2 more sources

The Epidemiology of Herpes Zoster in Immunocompetent, Unvaccinated Adults ≥50 Years Old: Incidence, Complications, Hospitalization, Mortality, and Recurrence

Journal of Infectious Diseases, 2019
Background Data on the epidemiology of herpes zoster (HZ), particularly in the unvaccinated immunocompetent population, are needed to assess disease burden and the potential impact of vaccination.
H. Tseng, K. Bruxvoort, B. Ackerson, Yi Luo, Hilary C Tanenbaum, Yun Tian, C. Zheng, Bianca Cheung, B. Patterson, Désirée A. M. van Oorschot, L. Sy   +10 more
semanticscholar   +1 more source

A Case of Hypercalcemia in an Immunocompetent Patient with Disseminated Mycobacterium marinum Infection with a Rain Barrel as the Most Likely Primary Source

European Journal of Case Reports in Internal Medicine, 2021
Infection with Mycobacterium marinum is common in fish, and so human infection usually arises from contact with contaminated water or fish. A solitary papulonodular lesion on a finger or hand is the typical presentation.
Wendy Uijtendaal, Rima Yohanna, Folkert Visser, Paul Ossenkoppele, Dorine Hess, Dennis Boumans   +5 more
doaj   +1 more source