Results 41 to 50 of about 1,620,419 (294)

Guillain-Barré Syndrome Following a Malignant Varicella in Immunocompetent Adult

, 2017
Varicella zoster virus (VZV) infection may trigger Guillain-Barre syndrome (GBS), but this is rare and almost always in the context of reactivation disease from latent VZV, ‘shingles’.
Gallouj S, Issoual K, Elmahi H, Mernissi FZ, Baybay H   +4 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Intestinal histoplasmosis in immunocompetent adults

World Journal of Gastroenterology, 2016
To present a retrospective analysis of clinical and endoscopic features of 4 cases of immunocompetent hosts with intestinal histoplasmosis (IH).Four immunocompetent adults were diagnosed with IH between October 2005 and March 2015 at West China Hospital of Sichuan University.
Lin-Lin, Zhu, Jin, Wang, Zi-Jing, Wang, Yi-Ping, Wang, Jin-Lin, Yang   +4 more
openaire   +2 more sources

Listeria Monocytogenes Meningitis in an Immunocompetent Adult [PDF]

, 2013
Listeria is an uncommon cause of acute bacterial meningitis. It usually affects neonates, elderly, immunocompromised,and pregnant women with only a few cases among healthy, immunocompetent adults. Food exposure also representsan important risk factor for
Reardon, Mark, Reardon, Peter
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Listerial rhombencephalitis in an immunocompetent young adult [PDF]

International Journal of Infectious Diseases, 2009
Listeria monocytogenes is a common cause of central nervous system infections, especially in immunosuppressed patients, infants and elderly people. Listerial rhombencephalitis is a rare and severe infection of the brainstem that is reported to have high mortality and frequent serious sequelae for survivors.
Kayaaslan, Bircan Ünal, Akıncı, Esragül, Bilen, Şule, Gözel, Mustafa Gökhan, Erdem, Deniz, Çevik, Mustafa Aydın, Bodur, Hürrem   +6 more
openaire   +2 more sources

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Enterovirus-Induced Severe Rhabdomyolysis and Acute Fulminant Liver Failure in an Immunocompetent Adult Requiring Liver Transplantation: A Case Report

, 2022
The authors report a case of a young healthy adult with severe rhabdomyolysis and acute fulminant liver failure with multiple organ dysfunction syndromes (MODS), possibly from an enterovirus infection. To the best of our knowledge, this is the first-ever
Tabbara, Abdul Kader, Chhina, Anoop, Angappan, Santhalakshmi, Pawloski, Jacob, Galusca, Dragos   +4 more
core   +2 more sources

Multiple cranial tuberculomas with meningitis and miliary tuberculosis in an immunocompetent adult

Northwestern Medical Journal
Miliary brain tuberculosis (TB) is a rare and highly lethal clinical form resulting from the extensive lymphohematogenous spread of Mycobacterium tuberculosis. Widespread brain involvement often suggests immunosuppression.
Ahmet Doğan, Hasan Tahsin Gözdaş, Tayibe Bal, Sultan Beste Şahin   +3 more
doaj   +1 more source