Results 241 to 250 of about 98,021 (296)

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Cost-Effectiveness of Plasma Microbial Cell-Free DNA Sequencing When Added to Usual Care Diagnostic Testing for Immunocompromised Host Pneumonia. [PDF]

Pharmacoeconomics
Sutton AJ, Lupu DS, Bergin SP, Holland TL, McAdams SA, Dadwal SS, Nguyen K, Nolte FS, Tremblay G, Perkins BA.   +9 more
europepmc   +1 more source

Extensive Intra-host evolution and T cell escape by SARS-CoV-2 in a 2.5-year persistent infection of an immunocompromised host

Guerra-Assunção JA, McErlean R, Townsend K, Flaxl LM, Tian SJ, Swadling L, Breuer J, Lowe DM.   +7 more
europepmc   +1 more source

Immunocompromised Host Pneumonia: Definitions and Diagnostic Criteria: An Official American Thoracic Society Workshop Report

Annals of the American Thoracic Society, 2023
Pneumonia imposes a significant clinical burden on people with immunocompromising conditions. Millions of individuals live with compromised immunity because of cytotoxic cancer treatments, biological therapies, organ transplants, inherited and acquired ...
Guang-Shing Cheng, Kristina Crothers, Stefano Aliberti   +2 more
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Pneumonia in the Immunocompromised Host

Seminars in Roentgenology, 2022
Pneumonia in the immunocompromised host can be devastating and can result from both common and opportunistic organisms. This paper examines the imaging findings in mostly opportunistic organisms which cause pneumonia in the immunocompromised host. Some organisms, such as tuberculosis, non-tuberculous mycobacteria, and influenza will also be discussed ...
Sowmiya, Murali, Aaron, Marks, Allen, Heeger, Farouk, Dako, Jennifer, Febbo   +4 more
openaire   +2 more sources

Competition for dominance within replicating quasispecies during prolonged SARS-CoV-2 infection in an immunocompromised host

Virus Evolution, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) emerge for their capability to better adapt to the human host aimed and enhance human-to-human transmission.
Francesca Caccuri, Serena Messali, Antonella De Palma   +2 more
exaly   +2 more sources

The Immunocompromised Host

Dermatologic Clinics, 1989
Infection still remains the most common immediate cause of death in the immunocompromised host. Because of the decreased host defenses leading not only to an increased susceptibility to a variety of opportunistic pathogens (in particular the fungi) but also to a decreased host inflammatory response and resultant clinical findings, infections in these ...
  +5 more sources

Fever in Immunocompromised Hosts

Emergency Medicine Clinics of North America, 2013
Fever is one of the most common reasons for the emergency department presentation of immunocompromised patients. Their differential diagnosis can be broad and includes rare or unexpected pathogens. Certain infectious causes of fever portend true emergencies; if they are not managed appropriately, rapid progression and death may ensue.
Devang M, Patel, David J, Riedel
openaire   +2 more sources

Mucormycosis in the immunocompromised host

Infection, 1983
We are presenting two typical case histories of mucormycosis in patients with acute leukaemia which illustrate some of the important features of this infection in compromised hosts. In such patients, mucormycosis is mostly pulmonary or widely disseminated and often has a rapidly fatal course.
S, Bhaduri, E, Kurrle, E, Vanek, R, Spanel   +3 more
openaire   +2 more sources

FEVER IN THE IMMUNOCOMPROMISED HOST

Emergency Medicine Clinics of North America, 1998
A broad classification of immune defects provides a framework for the approach to fever in the immunocompromised host. Practical, historical, and physical examination findings are reviewed, and common clinical scenarios are highlighted. A general initial work-up and treatment plan are outlined.
openaire   +2 more sources