Results 121 to 130 of about 51,504 (221)

Unmasking Oligosecretory multiple myeloma: a case report highlighting diagnostic pitfalls. [PDF]

Oxf Med Case Reports
Solórzano Flores C, Izaguirre A, Bravo Monroig E, Solano J.   +3 more
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 10, 18 February 2026.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Short-term storage conditions do not affect canine fecal cortisol and secretory immunoglobulin A concentrations. [PDF]

Sci Rep
Lenz OC, Powell L, Reinhard CL, Watson B.   +3 more
europepmc   +1 more source

Acute Acalculous Cholecystitis as the First Manifestation of Systemic Lupus Erythematosus in a Young Man: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Acute acalculous cholecystitis can rarely be the initial manifestation of systemic lupus erythematosus. Awareness of this atypical presentation is essential to avoid unnecessary surgical intervention. Prompt recognition and initiation of immunosuppressive therapy may resolve symptoms and help establish the correct underlying diagnosis.
Mohammad Mehdi Shadravan, Arman Ahmadzadeh, Ilad Alavi Darazam, Shahriar Nikpour, Maryam Haghighi Morad, Farid Javandoust Gharebagh, Sadaf Mahmoodkalaye, Setareh Mahmoodi, Legha Lotfollahi   +8 more
wiley   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Complementary Roles of Next-Generation Flow and Next-Generation Sequencing for Measurable Residual Disease Assessment in Multiple Myeloma. [PDF]

J Korean Med Sci
Park MS, Lim DJ, Kim HJ, Cho D, Yoon SE, Kim SJ, Kim K, Kim HY.   +7 more
europepmc   +1 more source

NLK facilitates Caspase‐8 activation to drive macrophage PANoptosis in sepsis

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
By promoting Caspase‐8 activation within the PANoptosome, NLK modulates pyroptotic, apoptotic, and necroptotic programs in macrophages, thereby driving inflammatory injury and multiorgan damage during sepsis. Abstract Mounting evidence indicates that macrophage PANoptosis—an integrated inflammatory cell‐death program comprising pyroptosis, apoptosis ...
Yun Xia, Ren‐qi Yao, Hui‐fan Liu, Guo‐qing Jing, Delida Aidebaike, Jing Zuo, Shi‐qi Wan, Die Wu, Peng‐yue Zhao, Hai‐long Gong, Xing Wang, Hui‐min Zhou, Ning Dong, Yao Wu, Shi Liu, Xiao‐jing Wu, Yong‐ming Yao, Xue‐min Song   +17 more
wiley   +1 more source

Periodontitis is associated with altered salivary anti-SARS-CoV-2 antibody patterns in vaccinated individuals. [PDF]

Front Immunol
Alkharaan H.
europepmc   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source