Results 11 to 20 of about 51,504 (221)

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Changes in Local Immunity Factors in Women with Pre-Existing Cervical Disease and Benign Ovarian Tumors

Galician Medical Journal, 2017
The objective of the research was to study the indices of local immunity in relation to the hormonal state of the body in women with benign ovarian tumors and pre-existing cervical diseases. Materials and methods. The concentration of major gonadotropic
Nazar Matviykiv
doaj   +1 more source

Correlation of total salivary secretory immunoglobulin A (SIgA) and mutans specific SIgA in children having different caries status

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2013
Background: Relation between secretory immunoglobulin A (SigA) and dental caries still imprecise. Studies have been conducted either for total SIgA or mutans specific SIgA with bizarre results.
Soumen Pal, Malay Mitra, Jiban Mishra, Subrata Saha, Bhaswar Bhattacharya   +4 more
doaj   +1 more source

Influence of Prolonged Storage Process, Pasteurization, and Heat Treatment on Biologically-active Human Milk Proteins

Pediatrics and Neonatology, 2013
The bioactive proteins in human milk may be influenced by prolonged storage process, pasteurization, and heat treatment. This study was conducted to evaluate the effects of these procedures.
Jih-Chin Chang, Chao-Huei Chen, Li-Jung Fang, Chi-Ren Tsai, Yu-Chuan Chang, Teh-Ming Wang   +5 more
doaj   +1 more source

بررسی تأثیر ماست حاوی پروبیوتیک بر غلظت ایمنوگلوبولین A ترشحی بزاق [PDF]

Journal of Mashhad Dental School, 2012
مقدمه: پروبیوتیک‏ها از طریق تنظیم ایمنی  موضعی اثرات سودمندی بر  سلامت دهان دارند.  هدف از این مطالعه ارزیابی تأثیر یک  فرآورده پروبیوتیک بر IgA بزاقی بود. مواد و روش ها: ایـن مطالعه تصادفی سه سوکور، بر روی 40 داوطلب سالم غیرسیگاری انجام گردید.
محمد واحدی, حمیدرضا عبدالصمدی, فاطمه احمدی متمایل, سوده طیبی, مهرداد حاجیلویی, عباس مقیم بیگی, پوراندخت داوودی   +6 more
doaj  

Evaluation of Salivary Secretory Immunoglobulin A Levels in Diabetic Patients and Association with Oral and Dental Manifestations

Sultan Qaboos University Medical Journal, 2015
Objectives: Oral and dental manifestations in diabetic patients can arise due to numerous factors, including elevated salivary secretory immunoglobulin A (s-IgA) levels.
Shahla Kakoei, Bahareh Hosseini, Ali-Akbar Haghdoost, Mojgan Sanjari, Ahmad Gholamhosseinian, Vahid F. N. Afshar   +5 more
doaj   +3 more sources

Intestinal fungi and antifungal secretory immunoglobulin A in Crohn’s disease

Frontiers in Immunology, 2023
The human gastrointestinal tract harbors trillions of commensal microorganisms. Emerging evidence points to a possible link between intestinal fungal dysbiosis and antifungal mucosal immunity in inflammatory bowel disease, especially in Crohn’s disease ...
Meng Sun, Jingyi Ju, Hongzhen Xu, Yufang Wang   +3 more
doaj   +1 more source

Higher Levels of Secretory IgA Are Associated with Low Disease Activity Index in Patients with Reactive Arthritis and Undifferentiated Spondyloarthritis

Frontiers in Immunology, 2017
IntroductionBoth reactive arthritis (ReA) and undifferentiated spondyloarthritis (uSpA) belong to the group of autoinflammatory diseases called spondyloarthritis (SpA).
Consuelo Romero-Sánchez, Consuelo Romero-Sánchez, Consuelo Romero-Sánchez, Fabián Salas-Cuestas, Wilson Bautista-Molano, Wilson Bautista-Molano, Juan M. Bello-Gualtero, Juan M. Bello-Gualtero, Ivonne Arias, Diana Marcela Castillo, Lorena Chila-Moreno, Rafael Valle-Oñate, Rafael Valle-Oñate, Daniel Herrera   +13 more
doaj   +1 more source

A CLINICAL CASE OF THE USE OF AN IMMUNOMODULATORY DRUG IN THE COMPLEX THERAPY OF SEVERE GENERALIZED PERIODONTITIS

Український стоматологічний альманах, 2020
Disorders in the periodontal tissues in generalized periodontitis have a significant negative impact on the patient’s somatic and psycho-emotional health, causing not only dental, but also medical and social difficulties.
G.М. Silenko, H.M. Sylenko
doaj   +1 more source

Evaluation of the secretory immunoglobulin A levels in the colostrum and milk of mothers of term and pre-trerm newborns

Brazilian Journal of Infectious Diseases
OBJECTIVE: To determine and to compare the levels of secretory immunoglobulin A in samples of colostrum and milk of mothers of term and preterm neonates. MATERIAL AND METHODS: The levels of secretory immunoglobulin A of 10 mothers of term neonates and 10
Edílson D. Araújo, Ana Katherine Gonçalves, Maria da Conceição Cornetta, Heleana Cunha, Maria L. Cardoso, Sirlei Siani Morais, Paulo C. Giraldo   +6 more
doaj   +1 more source