Results 21 to 30 of about 427,434 (307)

Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]

, 2014
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
Matthew Buckland (589995), Lorena Lorenzo (589997), Matthew Buckland, Dempster, J, Duraisingham Sai S., Longhurst Hilary J., Matthew Buckl, Sai S. Duraisingham, Sofia Grigoriadou (589998), Sai S Duraisingham, Hilary J Longhurst, John Dempster, Dempster John, Grigoriadou Sofia, Duraisingham, SS, Lorenzo, L, Buckland Matthew, Grigoriadou, S, Sofia Grigoriadou, Lorenzo Lorena, Sai S. Duraisingham (589994), Buckland, M, Longhurst, HJ, Lorena Lorenzo, John Dempster (589996), Buckland, MS, Hilary J. Longhurst (589999), Hilary J. Longhurst   +27 more
core   +1 more source

Non-functional immunoglobulin G transcripts in a case of hyper-immunoglobulin M syndrome similar to type 4 [PDF]

, 2004
86% of immunoglobulin G (IgG) heavy-chain gene transcripts were found to be non-functional in the peripheral blood B cells of a patient initially diagnosed with common variable immunodeficiency, who later developed raised IgM, whereas no non-functionally
Darlow, J.M., Farrell, A.M., John M. Darlow, David I. Stott, Stott, D.I., Alex M. Farrell   +5 more
core   +1 more source

The immunoglobulin κ gene families of human and mouse: a cottage industry approach [PDF]

, 2000
Some aspects of the work of our group on the human and mouse immunoglobulin κ genes are reviewed. The human κ locus contains a large duplication: a 600 kb C κ-proximal copy with 40 V κ genes is found in the close vicinity of a 440 kb C κ-distal copy with
Zachau, Hans G.
core   +1 more source

Cancer as a Dysfunctional Immune Disorder: Pro-Tumor TH1-like Immune Response and Anti-Tumor THαβ Immune Response Based on the Complete Updated Framework of Host Immunological Pathways

Biomedicines, 2022
Host immunological pathways are delicate to cope with different types of pathogens. In this article, we divide immunological pathways into two groups: Immunoglobulin G-related eradicable immunities and Immunoglobulin A-related tolerable immunities.
Yi-Hsin Lee, Kuo-Wang Tsai, Kuo-Cheng Lu, Li-Jane Shih, Wan-Chung Hu   +4 more
doaj   +1 more source

Clinical value of different anti-D immunoglobulin strategies for preventing Rh hemolytic disease of the fetus and newborn: A network meta-analysis.

PLoS ONE, 2020
BackgroundSeveral anti-D immunoglobulin strategies exist for preventing Rh hemolytic disease of the fetus and newborn. This study systematically assessed the clinical value of those therapeutic strategies.MethodsThe Web of Science, PubMed, EMBASE, China ...
Xiaohui Xie, Qiurong Fu, Ziwei Bao, Yi Zhang, Dan Zhou   +4 more
doaj   +1 more source

Immunoglobulin variable-region gene mutational lineage tree analysis: application to autoimmune diseases [PDF]

, 2006
Lineage trees have frequently been drawn to illustrate diversification, via somatic hypermutation (SHM), of immunoglobulin variable-region (IGV) genes. In order to extract more information from IGV sequences, we developed a novel mathematical method for ...
Gitit Shahaf, Dunn-Walters, D., Avital Steiman-Shimony, Michal Barak, Roshini S. Abraham, Ramit Mehr, Abraham, Roshini S., Mehr, Ramit, Steiman-Shimony, Avital, Barak, M., Steiman-Shimony, A., David I. Stott, Edelman, H., Edelman, Hanna, Barak, Michal, Stott, David I., Mehr, R., Shahaf, G., Dunn-Walters, Deborah, Deborah Dunn-Walters, Hanna Edelman, Shahaf, Gitit, Abraham, R.S., Stott, D.I.   +23 more
core   +1 more source

V_H replacement in rearranged immunoglobulin genes [PDF]

, 2005
Examples suggesting that all or part of the V_H segment of a rearranged V_HDJ_H may be replaced by all or part of another V_H have been appearing since the 1980s ...
Darlow, J.M., John M. Darlow, David I. Stott, Stott, D.I.   +3 more
core   +1 more source

Effects of Dietary Supplementation with Glutamine on the Immunity and Intestinal Barrier Gene Expression in Broiler Chickens Infected with Salmonella Enteritidis

Animals, 2022
The effects of glutamine (Gln) on immunity and intestinal barrier gene expression levels in broilers challenged with Salmonella Enteritidis were evaluated.
Qiujue Wu, Cong Wang, Jiahui Liao, Naizhi Hu, Binyao Cheng, Yan Ma, Yuqin Wang   +6 more
doaj   +1 more source

Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing

Life Science Alliance, 2023
Targeted capture sequencing (CapIG-seq) is a novel, efficient, and effective approach to examine multiple genomic alterations in ctDNA and bone marrow aspirates of patients with multiple myeloma.
Signy Chow, Olena Kis, David T Mulder, Arnavaz Danesh, Jeff Bruce, Ting Ting Wang, Donna Reece, Nizar Bhalis, Paola Neri, Peter JB Sabatini, Jonathan Keats, Suzanne Trudel, Trevor J Pugh   +12 more
doaj   +1 more source

HAEMAGGLUTINATION TECHNIQUES TO EVALUATE SPECIFIC SAFETY OF HUMAN INTRAVENOUS IMMUNOGLOBULINS

Медицинская иммунология, 2017
The safety issues of human intravenous immunoglobulin preparations are particularly important in modern pharmacotherapy for immunodeficiencies, hematologic and neurologic diseases, like as at transplant centers. Upon massive infusions of these media some
O. G. Kornilova, E. V. Paramonova, A. V. Nechaev, E. Yu. Kudasheva, I. V. Borisevich, N. I. Kishkurno   +5 more
doaj   +1 more source