Results 81 to 90 of about 608,665 (299)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Inadequate absorption of intramuscular anti-D immunoglobulin in a pregnant woman with a high body mass index

open access: yesEuropean Journal of Case Reports in Internal Medicine
Introduction: The D antigen is highly immunogenic, and alloanti-D antibodies in maternal blood may cause haemolytic disease of the foetus and newborn. Prophylactic administration of anti-D immunoglobulin (Ig) to D-negative pregnant women significantly ...
Ivica Marić, Klara Železnik
doaj   +1 more source

Dietary Artemisia ordosica extract alleviating immune stress in broilers exposed to lipopolysaccharide

open access: yesItalian Journal of Animal Science, 2017
This study was conducted to investigate the effect of Artemisia ordosica extract (AOE) on broilers challenged with lipopolysaccharide (LPS). 96 one-day-old Arbour Acres broilers were assigned in 2 × 2 factorial design, including two dietary treatments (0
Kun Li   +6 more
doaj   +1 more source

Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line [PDF]

open access: yes, 1984
We demonstrated that a subclone of an Abelson murine leukemia virus-transformed B-lymphoid cell line switched from mu to gamma 2b expression in vitro, by the classical recombination-deletion mechanism.
Alt, Frederick W.   +5 more
core  

Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]

open access: yes, 2017
Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco   +6 more
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Efficacy of intravenous human immunoglobulin in renal transplant recipients with moderate to severe pneumonia

open access: yesLinchuang shenzangbing zazhi, 2017
Objective To investigate the intravenous human immunoglobulin therapy in renal transplant recipients with moderate to severe pulmonary infection.Methods From October 2005 to July 2015,48 patients with moderate to severe pulmonary infection after renal ...
ZHU Bo-cheng   +4 more
doaj  

Expressions of immunoglobulin M and immunoglobulin D heavy chain in B-chronic lymphocytic leukemia and their correlation with CD38 expression

open access: yesIraqi Journal of Hematology, 2017
Background: B-chronic lymphocytic leukemia (CLL) is a monoclonal malignancy characterized by an accumulation of small mature-looking B lymphocytes in the blood, bone marrow, and other tissues.
Ghid Nahd Abdul Muhssen   +2 more
doaj   +1 more source

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

open access: yes, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte   +4 more
core   +1 more source

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