Results 91 to 100 of about 24,709 (211)

Screening of Human Antibody Fab Fragment against HBsAg and the Construction of its dsFv Form

International Journal of Biological Sciences, 2008
The objective of this study was to pursue the techniques involving the screening of the human antibody Fab fragment against hepatitis B virus surface antigen (HBsAg) and the construction of its disulfide-stabilized Fv fragment (dsFv).
Leili Jia, Jiyun Yu, Hongbin Song, Xuelin Liu, Weina Ma, Yuanyong Xu, Chuanfu Zhang, Shicun Dong, Qiao Li
doaj  

Depletion-restitution therapy of autoimmune rheumatic diseases. Part 2. Perspectives on bispecific antibodies

Современная ревматология
One of the most promising approaches to depletion-restitution therapy is the development and use of drugs based on bispecific monoclonal antibodies (bsAbs).
A. L. Maslyanskiy, D. A. Dibrov, A. M. Lila, A. V. Torgashina, E. G. Zotkin, M. Yu. Samsonov, G. A. Togizbayev   +6 more
doaj   +1 more source

Antibody degradation in tobacco plants: a predominantly apoplastic process. [PDF]

, 2011
BACKGROUND: Interest in using plants for production of recombinant proteins such as monoclonal antibodies is growing, but proteolytic degradation, leading to a loss of functionality and complications in downstream purification, is still a serious problem.
Drake, PM, Hehle, VK, Ma, JK, Paul, MJ, van Dolleweerd, CJ   +4 more
core   +2 more sources

The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of Immunoglobulin G [PDF]

, 2008
Recognition of immunoglobulin G (IgG) by surface receptors for the Fc domain of immunoglobulin G (Fc{gamma}), Fc{gamma}Rs, can trigger both humoral and cellular immune responses.
Bjorkman, Pamela J., Cheung, Evelyn J., Deis Trujillo, Robin, Farley, Alexander H., Hengel, Helmut, Reinhard, Henrike, Sprague, Elizabeth R.   +6 more
core   +3 more sources

Characterization of a monoclonal antibody that induces the acrosome reaction of sea urchin sperm. [PDF]

, 1987
A monoclonal antibody, J18/29, induces the acrosome reaction (AR) in spermatozoa of the sea urchin Strongylocentrotus purpuratus. J18/29 induces increases in both intracellular Ca2+ and intracellular pH similar to those occurring upon induction of the AR
Ebina, Y, Meinhof, CG, Schackmann, RW, Trimmer, JS, Vacquier, VD   +4 more
core  

Human immunodeficiency virus neutralizing antibodies and methods of use thereof [APPLICATION] [PDF]

, 2014
The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of ...
Bjorkman, Pamela J., Diskin, Ron, Nussenzweig, Michel, Scheid, Johannes   +3 more
core  

Blood preparations of humans and animals in terms of their quality, efficacy and safety

Биопрепараты: Профилактика, диагностика, лечение, 2018
The problems of quality and safety products derived from human blood plasma and hyperimmune animal sera as well as recombinant blood products resolved strict government regulation of their production processes.
M. V. Supotnitsky, A. A. Elapov, I. V. Borisevich, E. Yu. Kudasheva, V. I. Klimov, E. V. Lebedinskaya, L. V. Korsun, E. V. Gorbunova, V. G. Slobodayn, V. A. Merkulov, Yu. V. Olefir   +10 more
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Engineering of a recombinant fab antibody fragment against cortisol [PDF]

, 2013
The paper dwells upon the molecular cloning of genes coding the structure of mouse immunoglobulins, which can specifically bind steroid hormone cortisol.
Dormeshkin, D. O., Gilep, A. A., Ivashkevich, I. G., Leontiev, V. N.   +3 more
core  

Structural Insights From HIV-Antibody Co-Evolution And Related Immunization Studies [PDF]

, 2018
Human immunodeficiency virus type 1 (HIV-1) is a rapidly evolving pathogen and causes the acquired immunodeficiency syndrome (AIDS) in humans. There are ~30-35 million people infected with HIV around the world, and ~25 million have died since the first ...
Fera, Daniela, Morriss, Julia W., , \u2719, Nguyen, Diep, , \u2719, Ton, Therese, , \u2719, Zhou, Jeffrey O., , \u2719   +4 more
core   +1 more source

Publisher Correction: Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)2 fragments

Scientific Reports, 2023
Stephen Findlay‑Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Matthew Aldridge, Gareth Humphries, Holger Schuhmann, Didier Ngabo, Emma Rayner, Ashley Otter, Thomas Coleman, Bethany Hicks, Rachel Halkerston, Kostis Apostolakis, Stephen Taylor, Susan Fotheringham, Amanda Horton, Irene CanoCejas, Matthew Wand, Julia A. Tree, Mark Sutton, Victoria Graham, Roger Hewson, Stuart Dowall   +23 more
doaj   +1 more source