Results 241 to 250 of about 45,837 (320)

Dissecting antibody-dependent enhancement modulation by Fc-modified cross-neutralizing human monoclonal antibody. [PDF]

PeerJ
Injampa S, Benjathummarak S, Keadsanti S, Sootichote R, Puangmanee W, Yamanaka A, Sasaki T, Ramasoota P, Pitaksajjakul P.   +8 more
europepmc   +1 more source

Preclinical Characterization of SDFZ‐8, a Highly Potent HDAC1 Inhibitor, for Cancer Immunotherapy

MedComm, Volume 6, Issue 12, December 2025.
In this study, we designed a novel quinoline derivative as a potent HDAC inhibitor SDFZ‐8 and assessed its capability to enhance cancer immunotherapy, along with its potential synergistic effects with PD‐L1 blockade. ABSTRACT The histone deacetylases (HDACs) family plays a critical role in tumorigenesis and has been identified as having a significant ...
Yi Zhou, Jintong Du, Xue Li, Huajun Zhao, Junxin Xue, Yuchen Liu, Xinying Yang, Jinming Yu, Xuben Hou, Hao Fang   +9 more
wiley   +1 more source

Lectin-Fc(IgG) fusion proteins exhibit antifungal activity against the emerging multidrug-resistant pathogen <i>Candida auris</i>. [PDF]

Infect Immun
Mendoza SR, Honorato L, Cintra DS, Ferreira MdS, Zamith-Miranda D, Nosanchuk JD, Nimrichter L, Guimarães AJ.   +7 more
europepmc   +1 more source

Immunogenicity of heterologous Fc and Fab immunoglobulin fragments in rabbits, guinea-pigs and rats.

, 1967
R Binaghi, Rafaël Oriol, Yolande Boussac‐Aron   +2 more
openalex   +1 more source

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

The impact of Fc glycosylation on IgG susceptibility to hinge region chemical reduction: implications for the development of immunoassays. [PDF]

Biochem Biophys Rep
Susini V, Ursino S, Sanguinetti C, Botti A, Caponi L, Franzini M.   +5 more
europepmc   +1 more source

Computational analysis reveals non-consensus N-glycosylation sequons in antibody Fab region. [PDF]

MAbs
Qiu B, Chen E, Flick T, Letarte S.
europepmc   +1 more source

Sequencing of Polyclonal Antibodies by Integrating Intact Mass, Middle-Down, and De Novo Bottom-Up Mass Spectrometry. [PDF]

Mol Cell Proteomics
Xin L, Li W, Zhang S, Tran NH, Chen Z, Ma J, Peng C, Aihemaiti A, Hoffman K, Zhang X, Sun W, Li L, Wang Z, Li M, Shan B.   +14 more
europepmc   +1 more source

Cooperative effect between anti-PF4/H and anti-PF4 antibodies increases cell activation and thrombotic risk in HIT. [PDF]

Blood Adv
Billy S, Vayne C, Bertin O, Miquelestorena-Standley E, Charuel N, Dupont A, Coënon L, Pouplard C, Senis YA, Gruel Y, Rollin J.   +10 more
europepmc   +1 more source

Development and preclinical characterization of AMG 329: a human antibody neutralizing FLT3 ligand. [PDF]

MAbs
Lau-Kilby A, Gunsior M, Bartczak A, Chyou S, Hester J, Sims D, Xiao X, Pavlik P, Chen Y, Casey KA, Zerrouki K, Wang Q, Borrok MJ, Hansen AM, Rees WA.   +14 more
europepmc   +1 more source