Results 31 to 40 of about 161,876 (218)

The Immunobiology of Immunoglobulin G4

Seminars in Liver Disease, 2016
Human immunoglobulin G4 (IgG4) antibodies are in many ways unusual. In this review, an overview is given of the structural and functional aspects of IgG4 antibodies, the consequences of IgG4 antibody formation in various disease settings, and the factors involved in the regulation of IgG4 responses.
Laura C, Lighaam, Theo, Rispens
openaire   +3 more sources

A new location for pediatric immunoglobulin G4 related disease: the biceps muscle

The Turkish Journal of Pediatrics, 2020
Background. Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a systemic disorder of unknown etiology characterized by elevated serum IgG4 and tissue infiltration of IgG4-positive plasma cells. The disease was described in the pancreas, aorta,
Semanur Özdel, Mesiha Ekim, Gülşah Kaygusuz, Elif Çelikel, Göksel Vatansever, Nurdan Taçyıldız   +5 more
doaj   +1 more source

Immunoglobulin G4-related gastrointestinal diseases, are they immunoglobulin G4-related diseases

World Journal of Gastroenterology, 2013
In immunoglobulin G4 (IgG4)-related disease (RD), organ enlargement or nodular lesions consisting of abundant infiltration of lymphocytes and IgG4-positive plasma cells and fibrosis are seen in various organs. Although infiltration of many IgG4-positive plasma cells is detected in the gastric and colonic mucosa and major duodenal papilla of patients ...
Satomi, Koizumi, Terumi, Kamisawa, Sawako, Kuruma, Taku, Tabata, Kazuro, Chiba, Susumu, Iwasaki, Yuka, Endo, Go, Kuwata, Koichi, Koizumi, Tooru, Shimosegawa, Kazuichi, Okazaki, Tsutomu, Chiba   +11 more
openaire   +2 more sources

Immunoglobulin G4-Related Pancreatic and Biliary Diseases [PDF]

, 2013
BACKGROUND: Autoimmune pancreatitis and autoimmune cholangitis are new clinical entities that are now recognized as the pancreaticobiliary manifestations of immunoglobulin (Ig) G4-related ...
Alan N Barkun, Said Al-Busafi, Hisham Al-Dhahab, Julia McNabb-Baltar   +3 more
core   +1 more source

Pathologic significance of immunoglobulin G4-positive plasma cells in extrahepatic cholangiocarcinoma [PDF]

, 2012
Immunoglobulin G4-related sclerosing cholangitis is histologically characterized by the infiltration of immunoglobulin G4-positive plasma cells and sclerosing change. Moreover, several cases of carcinoma accompanied by immunoglobulin G4-positive cells in
Harada, Kenichi, 10115256, 25509, 30283112, Yasuni Nakanuma, 92, Kimura, Yasushi, 182, Kenichi Harada, Yasushi Kimura, Nakanuma, Yasuni   +10 more
core   +1 more source

Clinical significance of the detection of serum IgG4 and IgG4/IgG ratio in patients with thyroid-associated ophthalmopathy

Open Life Sciences, 2023
To evaluate the clinical significance of detecting serum IgG4 and the IgG4/IgG ratio in patients with thyroid-associated ophthalmopathy (TAO) and to explore whether high serum IgG4 levels and the IgG4/IgG ratio are associated with the severity and ...
Zhao JianGuo, Ge Yajing, Li Wenjing, Jiang Zipei   +3 more
doaj   +1 more source

Immunoglobulin G4-related disease in gastroenterology [PDF]

Vnitřní lékařství, 2021
IgG4-related disease is a recently defined clinical entity that can manifest itself in any organ. The most common gastrointestinal manifestations are diseases of the pancreas (autoimmune pancreatitis type 1) and biliary tree (IgG4-associated cholangitis); involvement of liver parenchyma is uncommon and the affection of tubular organs is very rare. IgG4-
Peter, Mačinga, Jana, Jarošová, Julius, Špičák, Tomáš, Hucl   +3 more
openaire   +2 more sources

Constrictive Pericarditis Caused by IgG4-Related Disease Requiring Pericardiectomy After Partial Response to Corticosteroids

JACC: Case Reports, 2020
Immunoglobulin G4–related disease is a systemic fibroinflammatory disease; pericardial involvement has occasionally been reported in publications.
Eugene Yuriditsky, MD, Aeshita Dwivedi, MD, Navneet Narula, MD, Leon Axel, MD, James M. Horowitz, MD, Mikhail Vaynblat, MD   +5 more
doaj   +1 more source

Immunoglobulin G subtypes-1 and 2 differentiate immunoglobulin G4-associated sclerosing cholangitis from primary sclerosing cholangitis

, 2020
Background Autoimmune pancreatitis is a special form of chronic pancreatitis with strong lymphocytic infiltration and two histopathological distinct subtypes, a lymphoplasmacytic sclerosing pancreatitis and idiopathic duct centric pancreatitis ...
Valente, Roberto, Löhr, J.-Matthias, Maetzel, Hartwig, Verbeke, Caroline Sophie, Hartwig Maetzel, Maier, Pia, Haas, Stephan L., Roberto Valente, Karouk Said, Caroline S Verbeke, Pia Maier, Maisonneuve, Patrick, J‐Matthias Löhr, Raffaella Pozzi‐Mucelli, Pozzi-Mucelli, Raffaella, Said, Karouk, Patrick Maisonneuve, Moro, Carlos F., Miroslav Vujasinovic, Vujasinovic, Miroslav, Stephan L Haas, Carlos F Moro   +21 more
core   +1 more source

Utility of serum immunoglobulin G4 in distinguishing immunoglobulin G4-associated cholangitis from cholangiocarcinoma [PDF]

Hepatology, 2011
Elevated serum immunoglobulin G4 (sIgG4) is a feature of autoimmune pancreatitis (AIP) and IgG4-associated cholangitis (IAC); a >2-fold increase in sIgG4 is considered highly specific for these disorders.
Abdul M, Oseini, Roongruedee, Chaiteerakij, Abdirashid M, Shire, Amaar, Ghazale, Joseph, Kaiya, Catherine D, Moser, Ileana, Aderca, Teresa A, Mettler, Terry M, Therneau, Lizhi, Zhang, Naoki, Takahashi, Suresh T, Chari, Lewis R, Roberts   +12 more
openaire   +2 more sources