Results 311 to 320 of about 225,064 (376)

An Unusual Case of Cutaneous Langerhans Cell Sarcoma Lacking S100 Expression: A Case Report and Review of the Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Randa Obid, Austin R. Green, Sion W. Jasmine, Rachel P. Kowal, Brooj Abro, Laura M. Warmke, Magdalena B. Czader, Ahmed K. Alomari, Carina A. Dehner   +8 more
wiley   +1 more source

Interruption of two immunoglobulin heavy-chain switch regions in murine plasmacytoma P3.26Bu4 by insertion of retroviruslike element ETn.

, 1987
Briton E. Shell, Paul F. Szurek, Wesley A. Dunnick   +2 more
openalex   +1 more source

Metabolomic and proteomic stratification of equine osteoarthritis

Equine Veterinary Journal, EarlyView.
Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson, Marie M. Phelan, Eva Caamaño‐Gutiérrez, Peter D. Clegg, Luis M. Rubio‐Martinez, Mandy J. Peffers   +5 more
wiley   +1 more source

A Case of T-Cell Large Granular Lymphocytic Leukemia and Renal Immunoglobulin Heavy Chain Amyloidosis. [PDF]

Am J Case Rep, 2019
Fu J, Lee LX, Zhou P, Fogaren T, Varga C, Comenzo RL.   +5 more
europepmc   +1 more source

The 48-base-long primordial building block of immunoglobulin light-chain variable regions is complementary to the primordial building block of heavy-chain variable regions.

, 1982
Shigeo Ohno, Takeshi Matsunaga
openalex   +1 more source

Synovial fluid alpha‐2‐macroglobulin, gelsolin and lubricin distinguish between osteoarthritic and healthy equine joints

Equine Veterinary Journal, EarlyView.
Abstract Background Synovial fluid (SF) is an ideal sentinel fluid for osteoarthritis (OA) diagnosis and prognostication due to its critical homeostatic role, proximity to articular tissues and immune cell composition. Untargeted proteomics enable identification of soluble markers for diagnostic and therapeutic applications while minimising bias ...
Erica J. Secor, Sydney J. Womack, Machiel P. Ysebaert, Marshall J. Colville, Heidi L. Reesink   +4 more
wiley   +1 more source

Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease. [PDF]

Cell Immunol, 2019
Jones BG, Penkert RR, Surman SL, Sealy RE, Pelletier S, Xu B, Neale G, Maul RW, Gearhart PJ, Hurwitz JL.   +9 more
europepmc   +1 more source

Evaluation of MYD88 p.L265P detection by digital droplet polymerase chain reaction in cerebrospinal fluid for integrated diagnosis of primary large B‐cell lymphoma of the central nervous system

British Journal of Haematology, EarlyView.
Vincent Harlay, Catherine Gallardo, Nathalie Beaufils, Alexandre Astier, Benoit Testud, Amira Amri, Shirley Fritz, Norman Abbou, Philippe Robert, Jeremy Garcia, Patrice Roll, L'houcine Ouafik, Laurence Schenone, Gregorio Petrirena, Alexandre Bertucci, Céline Bequet, Olivier Chinot, Emeline Tabouret, Isabelle Nanni, Romain Appay, Elise Kaspi, Diane Frankel   +21 more
wiley   +1 more source

Profiling of Anti‐FVIII Antibodies in Acquired Haemophilia A: ‘Insights into Domain Specificity, Isotype Variability, and Clinical Correlations’

Haemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder caused by autoantibodies against coagulation factor VIII (FVIII), resulting in significant bleeding risks. Aim To characterize the anti‐FVIII antibody profile in AHA patients by assessing isotypes, subclasses, and correlations with key clinical parameters.
Ann‐Cristin Berkemeier, Isabell Matuschek, Katrin Hartlieb, Thilo Albert, Natascha Marquardt, Johannes Oldenburg, Behnaz Pezeshkpoor   +6 more
wiley   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source