Results 111 to 120 of about 394,026 (356)

Biochemical and aggregation analysis of Bence Jones proteins from different light chain diseases [PDF]

Deposition of immunoglobulin light chains is a result of clonal proliferation of monoclonal plasma cells that secrete free immunoglobulin light chains, also called Bence Jones proteins (Bence Jones proteins).
Bellotti V, Buxbaum J, Fink A L, Gertz M A, Goto Y, Hurle M R, Khurana R, Kim Y, Laura A. Sikkink, Makin O S, Marina Ramirez-Alvarado, Pace C N, Perfetti V, Ramirez-Alvarado M, Ramirez-Alvarado M, Ramirez-Alvarado M, Ramirez-Alvarado M, Roussel A, Royer B, Semisotnov G V, Sezer O, Souillac P O, Souillac P O, Souillac P O, Stevens F J, Vidal R, Wetzel R   +26 more
core   +2 more sources

Cerebrospinal Fluid Analysis in Multiple Sclerosis Diagnosis: An Update [PDF]

, 2019
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS) with brain neurodegeneration. MS patients present heterogeneous clinical manifestations in which both genetic and environmental factors are involved ...
Bruna Lo Sasso, Chiara Bellia, Giulia Bivona, Luisa Agnello, Marcello Ciaccio   +4 more
core   +1 more source

Herbal Formula Yi‐Fei‐Jie‐Du‐Tang Regulates Epithelial‐Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A‐Mediated Ferroptosis

Advanced Biology, Volume 9, Issue 3, March 2025.
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang, Die Yang, Chengjia Yuan, Yang Wu, Qingying Wang, Yongjian Wu, Xiaochun Zhang   +6 more
wiley   +1 more source

Bence-Jones Proteins and Light Chains of Immunoglobulins [PDF]

, 1969
A Solomon, Carla L. McLaughlin
openalex   +2 more sources

A prospective study of nutritional status in immunoglobulin light chain amyloidosis

Haematologica, 2013
Weight loss is common in systemic immunoglobulin light chain amyloidosis but there are limited data on the impact of nutritional status on outcome.
Prayman T. Sattianayagam, Thirusha Lane, Zoe Fox, Aviva Petrie, Simon D.J. Gibbs, Jennifer H. Pinney, Signe S. Risom, Dorota M. Rowczenio, Ashutosh D. Wechalekar, Helen J. Lachmann, Janet A. Gilbertson, Philip N. Hawkins, Julian D. Gillmore   +12 more
doaj   +1 more source

Phase Transition in a Model of Y-Shaped Molecules [PDF]

arXiv, 2014
In recent years the statistical mechanics of non-spherical molecules, such as polypeptide chains and protein molecules, has garnered considerable attention as their phase behavior has important scientific and health implications. One example is provided by immunoglobulin, which has a "Y"-shape.
arxiv  

Evolution and Mutations of Beta 2 Microglobulin [PDF]

arXiv, 2022
Here we examine the evolution of beta-2 microglobulin in terms of its hydropathic shapes, a theoretical construct that has revealed important trends. The dynamics of many proteins are largely driven by interactions between the protein itself and the thin water film that covers it.
arxiv  

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

A wash-free, dip-type fiber optic plasmonic (DiP) assay for sub-zeptomole analyte detection [PDF]

arXiv, 2018
This study demonstrates a rapid, wash-free dip-type fiber optic plasmonic sandwich (DiP) assay capable of zeptomole analyte detection and 6-orders of wide dynamic range. The DiP assay is realized on a compact U-bent fiber optic probe surface by dipping the antibody functionalized probe into a mixture of sample solution and AuNP labeled reagent.
arxiv  

Light chains of immunoglobulins: structural-genetic correlates [PDF]

Blood, 1986
WITHIN the past decade, studies by molecular geneticists on the composition and organization of immunoglobulin (Ig)-coding genes at the DNA level have vastly increased our understanding of the genetic mechanisms responsible for generating antibody diversity and for linking Ig synthesis to cellular differentiation.
openaire   +4 more sources