Results 271 to 280 of about 394,026 (356)

Dual Role of CRABP2 in Colorectal Cancer: Oncogenesis via Nuclear RB1 and Cytoplasmic AFG3L2/SLC25A39 Axis, While Limiting Liver Metastasis through Cytoplasmic AFG3L2/PINK1/Parkin‐Mediated Mitophagy

Advanced Science, EarlyView.
CRABP2 plays a dual role in colorectal cancer: it promotes proliferation and suppresses apoptosis through the nuclear CRABP2/RB1 axis and the cytoplasmic AFG3L2/SLC25A39 axis. Meanwhile, it inhibits colorectal liver metastasis via AFG3L2/PINK1/Parkin‐mediated mitophagy.
Chuanxin Tian, Sheng Yang, Chuan Zhang, Renzhong Zhu, Chen Chen, Xiaowei Wang, Dongsheng Zhang, Qingyang Sun, Hengjie Xu, Hongxu Nie, Yue Zhang, Dongjian Ji, Junwei Tang, Kangpeng Jin, Yueming Sun   +14 more
wiley   +1 more source

Refractory IgM AL amyloidosis with massive soft tissue tumors: Rescue with zanubrutinib. A case report

Current Problems in Cancer: Case Reports
Waldenström macroglobulinemia (WM) is a rare indolent B-cell non-Hodgkin lymphoma with lymphoplasmacytic morphology, associated with immunoglobulin M (IgM) monoclonal gammopathy. The coexistence of WM and immunoglobulin light chain (AL) amyloidosis is an
Piotr Jachimowski, Łukasz Ciulkiewicz, Mateusz Ziarkiewicz, Bogna Ziarkiewicz-Wróblewska, Marta Legatowicz-Koprowska, Krzysztof Jamroziak   +5 more
doaj  

Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. [PDF]

Bioorg Med Chem Lett, 2022
Yan NL, Nair R, Chu A, Wilson IA, Johnson KA, Morgan GJ, Kelly JW.   +6 more
europepmc   +1 more source

Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors [PDF]

, 1992
Pièrre Aucouturier, Ahmed Amine Khamlichi, J L Preud'homme, Marc Bauwens, Guy Touchard, Michel Cogné   +5 more
openalex   +1 more source

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Advanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu   +22 more
wiley   +1 more source

Chinese consensus on the diagnosis and treatment of immunoglobulin light-chain cardiac amyloidosis. [PDF]

Chin Med J (Engl)
Shen K, Tian Z, Gao Y, Wang Y, Huo L, Li J, Zhang Y, Zhang S, Chinese Society of Rare Diseases and Rare Diseases Branch of China Research Hospital Association.   +8 more
europepmc   +1 more source

Identification of Immunoglobulin Light Chains in Canine Extramedullary Plasmacytomas by Thioflavine T and Immunohistochemistry [PDF]

, 1991
Steven R. Brunnert, Norman H. Altman
openalex   +1 more source

Recent Advances in Xenes Based FET for Biosensing Applications

Advanced Science, EarlyView.
Xenes (monoelemental 2D materials like graphene, phosphorene, tellurene) enable ultrasensitive FET (Field‐Effect Transistor) biosensors due to their tunable bandgap, high carrier mobility, and large surface area. Advances in synthesis (CVD, MBE) and functionalization allow detection of DNA/RNA (via CRISPR‐Cas systems), proteins, small molecules, and ...
Huide Wang, Chen Wang, Yule Zhang, Ziqian Wang, Yihan Zhu, Yun Wang, Xiangqian Hong, Han Zhang, Ning Fan, Meng Qiu   +9 more
wiley   +1 more source

A Rare Case of Non-IgM Lymphoplasmacytic Lymphoma with Unusual Lack of Immunoglobulin Light Chain Production. [PDF]

Am J Case Rep
Yin J, Bains A, Alsammak M, Fu JJ.
europepmc   +1 more source

Evolution of immunoglobulin light chains: cDNA clones specifying sandbar shark constant regions.

, 1989
Samuel F. Schluter, Valerie S. Hohman, Allen B. Edmundson, John J. Marchalonis   +3 more
openalex   +1 more source