Results 181 to 190 of about 248,637 (315)

Transcription in vitro of immunoglobulin kappa light chain genes in isolated mouse myeloma nuclei and chromatin.

, 1976
M. Mitchell Smith, Ru Chih C. Huang
openalex   +1 more source

Independent folding of the variable and constant halves of a lambda immunoglobulin light chain [PDF]

, 1972

openalex   +1 more source

Dual Role of CRABP2 in Colorectal Cancer: Oncogenesis via Nuclear RB1 and Cytoplasmic AFG3L2/SLC25A39 Axis, While Limiting Liver Metastasis through Cytoplasmic AFG3L2/PINK1/Parkin‐Mediated Mitophagy

Advanced Science, EarlyView.
CRABP2 plays a dual role in colorectal cancer: it promotes proliferation and suppresses apoptosis through the nuclear CRABP2/RB1 axis and the cytoplasmic AFG3L2/SLC25A39 axis. Meanwhile, it inhibits colorectal liver metastasis via AFG3L2/PINK1/Parkin‐mediated mitophagy.
Chuanxin Tian, Sheng Yang, Chuan Zhang, Renzhong Zhu, Chen Chen, Xiaowei Wang, Dongsheng Zhang, Qingyang Sun, Hengjie Xu, Hongxu Nie, Yue Zhang, Dongjian Ji, Junwei Tang, Kangpeng Jin, Yueming Sun   +14 more
wiley   +1 more source

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes [PDF]

, 1982
O. Wesley McBride, P. Heiter, GF Hollis, Daniel Swan, MC Otey, Philip Leder   +5 more
openalex   +1 more source

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

Advanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao, Siwen Chen, Hua Chao, Zihao Li, Hao Yang, Dongying Chen, Sifang Li, Shuai Zhang, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Tangming Guan, Yiwen Zhang, Wende Li, Hui Liu   +16 more
wiley   +1 more source

Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis. [PDF]

Sci Rep
Bézard M, Vartanian-Grimaldi JS, Henri J, Calin D, Zaroui A, Kharoubi M, Damy T, Agbulut O, Kordeli E.   +8 more
europepmc   +1 more source

Mechanistic Insights into the Early Events in the Aggregation of Immunoglobulin Light Chains. [PDF]

Biochemistry, 2019
Misra P, Blancas-Mejia LM, Ramirez-Alvarado M.   +2 more
europepmc   +1 more source

A Structural Feature of Human Immunoglobulin Light Chains

, 1972
F. Anders Karlsson, Per A. Peterson, Ingemar Berggård   +2 more
openalex   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

Coronary health index based on immunoglobulin light chains to assess coronary heart disease risk with machine learning: a diagnostic trial. [PDF]

J Transl Med
Ren W, Zhang Z, Wang Y, Wang J, Li L, Shi L, Zhai T, Huang J.   +7 more
europepmc   +1 more source