Immunoglobulin Y for Potential Diagnostic and Therapeutic Applications in Infectious Diseases [PDF]
Frontiers in Immunology, 2021 Antiviral, antibacterial, and antiparasitic drugs and vaccines are essential to maintaining the health of humans and animals. Yet, their production can be slow and expensive, and efficacy lost once pathogens mount resistance.
Lucia Lee +4 more
doaj +3 more sources
Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19 [PDF]
Frontiers in Immunology, 2022 COVID-19 emergency use authorizations and approvals for vaccines were achieved in record time. However, there remains a need to develop additional safe, effective, easy-to-produce, and inexpensive prevention to reduce the risk of acquiring SARS-CoV-2 ...
Lyn R. Frumkin +29 more
doaj +4 more sources
SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice [PDF]
PLoS Pathogens, 2022 Safe, passive immunization methods are required against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants. Immunization of chickens with antigen is known to induce specific IgY antibodies concentrated in the egg yolk and has a
Sherif A. El-Kafrawy +11 more
doaj +4 more sources
Comprehensive N-Glycan Profiling of Avian Immunoglobulin Y. [PDF]
PLoS ONE, 2016 Recent exploitation of the avian immune system has highlighted its suitability for the generation of high-quality, high-affinity antibodies to a wide range of antigens for a number of therapeutic and biotechnological applications.
Sarah Gilgunn +7 more
doaj +3 more sources
Effect of microencapsulation of egg yolk immunoglobulin Y by sodium alginate/chitosan/sodium alginate on the growth performance, serum parameters, and intestinal health of broiler chickens. [PDF]
Anim Biosci, 2023 Objective Egg yolk immunoglobulin (IgY) is an antibiotic alternative to prevent and fight intestinal pathogenic infections. This study aimed to investigate the effects of sodium alginate/chitosan/sodium alginate IgY microcapsules on the growth ...
Jin Y +6 more
europepmc +2 more sources
Chicken Enterococcus faecalis-induced immunoglobulin Y as a prophylactic and therapeutic agent against streptococcosis in red tilapia (Oreochromis hybrid) [PDF]
Veterinary World, 2023 Background and Aim: Streptococcosis is a common bacterial disease in red tilapia, in which Enterococcus faecalis infection has not been widely reported. This study aimed to evaluate the efficacy of pellets that contain chicken E.
Rifky Rizkiantino +9 more
doaj +2 more sources
IgY antibodies against cytolysin reduce ethanol-induced liver disease in mice. [PDF]
Hepatology, 2023 Background and Aims: Patients with severe alcohol-associated hepatitis have high morbidity and mortality. Novel therapeutic approaches are urgently needed.
Cabré N +11 more
europepmc +2 more sources
Simple and efficient protocol for immunoglobulin Y purification from chicken egg yolk. [PDF]
Poult Sci, 2021 Besides being a common food component broadly consumed worldwide, egg yolk immunoglobulin Y (IgY) has essential therapeutic potentials. In fact, in a time of ever-increasing risk of antibiotic resistance, it is crucial to find new ways to battle ...
Redwan EM, Aljadawi AA, Uversky VN.
europepmc +2 more sources
Latest Findings in Immunoglobulin Y Technologies and Applications. [PDF]
Int J Mol SciImmunoglobulin Y (IgY), the major antibody class in birds, has gained increasing attention in recent years as a versatile and ethically sustainable alternative to mammalian immunoglobulins.
Capotă R +4 more
europepmc +2 more sources
Formation and preliminary characterization of mercury-reactive immunoglobulin Y antibodies in laying hens using HgCl₂–protein hapten conjugates [PDF]
Veterinary WorldBackground and Aim: Mercury (Hg) is a persistent environmental toxin that poses significant risks to animal and human health through contaminated feed, water, and ecosystems.
Wayan Wariata +3 more
doaj +2 more sources