Results 1 to 10 of about 410,635 (273)

Immunoglobulin Y for Potential Diagnostic and Therapeutic Applications in Infectious Diseases [PDF]

Frontiers in Immunology, 2021
Antiviral, antibacterial, and antiparasitic drugs and vaccines are essential to maintaining the health of humans and animals. Yet, their production can be slow and expensive, and efficacy lost once pathogens mount resistance.
Lucia Lee, Kate Samardzic, Michael Wallach, Lyn R. Frumkin, Daria Mochly-Rosen   +4 more
doaj   +5 more sources

Comprehensive N-Glycan Profiling of Avian Immunoglobulin Y. [PDF]

PLoS ONE, 2016
Recent exploitation of the avian immune system has highlighted its suitability for the generation of high-quality, high-affinity antibodies to a wide range of antigens for a number of therapeutic and biotechnological applications.
Sarah Gilgunn, Silvia Millán Martín, Mark R Wormald, Julia Zapatero-Rodríguez, Paul J Conroy, Richard J O'Kennedy, Pauline M Rudd, Radka Saldova   +7 more
doaj   +5 more sources

SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice [PDF]

PLoS Pathogens, 2022
Safe, passive immunization methods are required against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants. Immunization of chickens with antigen is known to induce specific IgY antibodies concentrated in the egg yolk and has a
Sherif A. El-Kafrawy, Abby Odle, Aymn T. Abbas, Ahmed M. Hassan, Umama A. Abdel-dayem, Arooj K. Qureshi, Lok-Yin Roy Wong, Jian Zheng, David K. Meyerholz, Stanley Perlman, Alimuddin Zumla, Esam I. Azhar   +11 more
doaj   +6 more sources

Immunoglobulin Y Specific for SARS-CoV-2 Spike Protein Subunits Effectively Neutralizes SARS-CoV-2 Infectivity and Ameliorates Disease Manifestations In Vivo [PDF]

Biomedicines, 2022
(Background) The coronavirus disease 2019 (COVID-19) that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carries high infectivity and mortality. Efficient intervention strategies are urgently needed. Avian immunoglobulin Y (IgY)
Chia-Tsui Yeh, Chia-Ying Lee, Yi-Jung Ho, Sin-An Chen, Liang-Yu Chen, Ping-Cheng Liu, Yuan-Fan Chin, An-Yu Chen, Po-Shiuan Hsieh, Yi-Jen Hung, Cheng-Cheung Chen, Yu-Chie Wang, Guan-Chiun Lee   +12 more
doaj   +2 more sources

Chicken Enterococcus faecalis-induced immunoglobulin Y as a prophylactic and therapeutic agent against streptococcosis in red tilapia (Oreochromis hybrid) [PDF]

Veterinary World, 2023
Background and Aim: Streptococcosis is a common bacterial disease in red tilapia, in which Enterococcus faecalis infection has not been widely reported. This study aimed to evaluate the efficacy of pellets that contain chicken E.
Rifky Rizkiantino, Fachriyan Hasmi Pasaribu, Retno Damajanti Soejoedono, Wyanda Arnafia, Dinda Reisinta, Rifaldi Iqbal Yadiansyah, Beni Halalludin, Yunita Ardini, Granita Khanaria, I Wayan Teguh Wibawan   +9 more
doaj   +2 more sources

Evaluation of antimicrobial efficacy of immunoglobulin Y (IgY) against periodontal biofilm. [PDF]

J Oral Maxillofac Pathol, 2023
Background and Objectives: To determine the action of immunoglobulin Y (IgY) on supragingival microbiota and on subgingival microbiota in patients with gingivitis and periodontitis through microbial reduction assay. Methodology: 40 systemically healthy patients were divided into two
Sindhu BU, Praveen S, Sandeep JN, Avinash JL, Rajiv NP, Rudraswamy S.   +5 more
europepmc   +3 more sources

Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19 [PDF]

Frontiers in Immunology, 2022
COVID-19 emergency use authorizations and approvals for vaccines were achieved in record time. However, there remains a need to develop additional safe, effective, easy-to-produce, and inexpensive prevention to reduce the risk of acquiring SARS-CoV-2 ...
Lyn R. Frumkin, Michaela Lucas, Curtis L. Scribner, Nastassja Ortega-Heinly, Jayden Rogers, Gang Yin, Trevor J. Hallam, Alice Yam, Kristin Bedard, Rebecca Begley, Courtney A. Cohen, Courtney A. Cohen, Catherine V. Badger, Shawn A. Abbasi, John M. Dye, Brian McMillan, Michael Wallach, Michael Wallach, Traci L. Bricker, Astha Joshi, Adrianus C. M. Boon, Suman Pokhrel, Benjamin R. Kraemer, Lucia Lee, Stephen Kargotich, Mahima Agochiya, Tom St. John, Daria Mochly-Rosen, Daria Mochly-Rosen, Daria Mochly-Rosen   +29 more
doaj   +3 more sources

Latest Findings in Immunoglobulin Y Technologies and Applications. [PDF]

Int J Mol Sci
Immunoglobulin Y (IgY), the major antibody class in birds, has gained increasing attention in recent years as a versatile and ethically sustainable alternative to mammalian immunoglobulins. IgY has demonstrated strong potential in diagnostics, prophylaxis, and therapy across a wide range of fields, including infectious diseases, allergy management ...
Capotă R, Ciaușu-Sliwa D, Bostănaru-Iliescu AC, Năstasă V, Mareș M.   +4 more
europepmc   +2 more sources

Comparative study on encapsulation and sustained release of anti-Campylobacter jejuni Immunoglobulin Y Using Various pH-Responsive Beads [PDF]

Poultry Science
To protect egg yolk immunoglobulin (IgY) from degradation by pepsin and acidic conditions during oral administration, Campylobacter jejuni (C. jejuni)-specific IgY was encapsulated in polypeptide beads using various methodologies.
Nazanin Soltani, Shaban Rahimi, Ebrahim Vasheghani-Farahani, Bahareh Eskandari, Jesse Grimes   +4 more
doaj   +2 more sources

Simple and efficient protocol for immunoglobulin Y purification from chicken egg yolk. [PDF]

Poult Sci, 2021
Besides being a common food component broadly consumed worldwide, egg yolk immunoglobulin Y (IgY) has essential therapeutic potentials. In fact, in a time of ever-increasing risk of antibiotic resistance, it is crucial to find new ways to battle infection, and oral administration of preformed specific antibodies represents one of the most attractive ...
Redwan EM, Aljadawi AA, Uversky VN.
europepmc   +5 more sources