Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]
BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham +105 more
core +2 more sources
Kawasaki disease shock syndrome rescued by a combination of extracorporeal membrane oxygenation, steroids, and intravenous immunoglobulin [PDF]
Kawasaki disease shock syndrome (KDSS) is defined as a sustained decrease in systolic blood pressure or signs of poor perfusion. Some children with KDSS are refractory to conventional therapy, such as intravenous immunoglobulin (IVIG).
Chanyoung Chung +4 more
doaj +1 more source
Single-domain antibodies and their formatting to combat viral infections [PDF]
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies +4 more
core +2 more sources
INTRAVENOUS IMMUNOGLOBULIN APPLICATION IN CLINICAL PRACTICE
The article gives data on the structure and function of immunoglobulins. Given the multitude of mechanisms of their action, indications to their use are constantly expanding.
T. V. Latysheva, E. A. Latysheva
doaj +1 more source
Varicella zoster virus (VZV) pneumonia is associated with significant mortality, especially in the immunocompromised host. VZV-specific immunoglobulins (VZIG) are currently used as post-exposure prophylaxis for at-risk patients, but not as adjunctive ...
Davide Mangioni +5 more
doaj +1 more source
Continuous increase of immunoglobulin therapy in Iceland
Background: The use of immunoglobulin treatment has been increasing for various indications. The objective of this study was to evaluate clinical use of immunoglobulin therapy in Iceland, estimate off-label usage and describe possible changes in this ...
Valgeir Steinn Runólfsson +5 more
doaj +1 more source
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies [PDF]
During recent years, an increasing number of neuromuscular diseases have been recognized either to be caused primarily by autoimmune mechanisms, or to have important autoimmune components.
Oliveira, Acary Souza Bulle +2 more
core +3 more sources
Methylprednisolone versus intravenous immune globulin as an initial therapy in adult primary immune thrombocytopenia [PDF]
Background/Aims Few studies have addressed whether there are differences in clinical efficacy between intravenous methylprednisolone (methyl-Pd) and intravenous immunoglobulin (IVIg) use.
Chul Hee Kim +9 more
doaj +1 more source
Subcutaneous immunoglobulin in treating inflammatory neuromuscular disorders
Objective: Intravenous immunoglobulin administration has long been used in the treatment of autoimmune neuromuscular disorders. Immunoglobulins may be administered by intramuscular, intravenous or subcutaneous routes.
Min-Suk Yoon +2 more
doaj +1 more source
INTRAVENOUS IMMUNOGLOBULINS: MECHANISMS OF THERAPEUTIC EFFECTS
Intravenous immunoglobulins (IVIG) are currently the most widely used immunobiological drug derived from donor blood. The IVIG preparations contain antibodies, mostly, of IgG class, obtained from plasma pools of 3,000 to 15,000 donors (over 1000 donors ...
V. A. Lazanovich, E. V. Prosekova
doaj +1 more source

