Prevalence of FoxP3+ Cells in Canine Tumours and Lymph Nodes Correlates Positively with Glucose Transporter 1 Expression [PDF]
A. Hibbert+67 more
core +2 more sources
Multisystemic Disease and Septicemia Caused by Presumptive Burkholderia pseudomallei in American Quarter Horse, Florida, USA. [PDF]
Thornton JJ+3 more
europepmc +1 more source
The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang+16 more
wiley +1 more source
TERT Immunohistochemistry in Thin Melanomas Compared to Melanocytic Nevi. [PDF]
Zboraș I+8 more
europepmc +1 more source
Genetics‐Based Targeting Strategies for Precise Neuromodulation
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He+11 more
wiley +1 more source
HPV-associated squamous cell carcinoma and adenocarcinoma in distinct cervical sites: a case report. [PDF]
Chen H+15 more
europepmc +1 more source
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou+11 more
wiley +1 more source
piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang+16 more
wiley +1 more source
Comparative study of feline spinal cord tumors for distinction between peripheral nerve sheath tumor and meningioma. [PDF]
Saito R, Chambers JK, Uchida K.
europepmc +1 more source