Results 281 to 290 of about 1,228,272 (336)

Corrigendum to "Myoepithelioma-like hyalinizing epithelioid tumors of the palm: A case report". [PDF]

J Int Med Res
europepmc   +1 more source

Morphometric analysis and immunobiological investigation of <i>Indigofera oblongifolia</i> on the infected lung with <i>Plasmodium chabaudi</i>. [PDF]

Open Life Sci
Murshed M, Al-Tamimi J, Ebaid H, Al-Quraishy S.   +3 more
europepmc   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

Peripheral alveolar macrophages express more ACE2 immunoreactivity than in hilar area in human autopsied lung. [PDF]

BMC Res Notes
Nogami M, Mutsuro-Aoki H, Hoshi T, Toukairin Y, Arai T, Nishio T.   +5 more
europepmc   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Role of immunohistochemistry in lymphoma

Indian Journal of Medical and Paediatric Oncology, 2010
openaire   +4 more sources

Single‐Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients

Advanced Science, EarlyView.
scRNA sequencing reveals distinct tumor ecosystem features in CAYA‐PTC, marked by enriched CD4T_Tfh, CD8T_Tex cells, and rapid malignant thyrocyte differentiation (absent of mild‐state BRAF‐like population) toward invasive states. Prominent emCAF_LAMP5 populations interact with endothelial cells and thyrocytes facilitate angiogenesis and metastasis ...
Kai Guo, Lingyi Yang, Zirui Huang, Kai Qian, Yuan Shi, Mengjia Fei, Yuan Feng, Zixian Chen, Ming Qiu, Linglin Tang, Anqi Li, Zhibao Lv, Jiangbin Liu, Zhou Chen, Kuiran Dong, Zhuoying Wang   +15 more
wiley   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

The Application of Giemsa Staining in Identifying <i>Helicobacter pylori</i> in Oral Biopsies: A Comparative Study with Immunohistochemistry.

J Pharm Bioallied Sci
Rajak VS, Srivastava AK, Yadav SS, Mehta A.   +3 more
europepmc   +1 more source

The Prediction Model for Triple-Negative Breast Cancer Prognosis and Immunotherapy Efficacy Based on Single-Cell Sequencing of CD8+ T cells. [PDF]

J Cancer
Yi J, Qiao Y, Xiong Z, Feng J, Zouxu X, Zeyu S, Wang X.   +6 more
europepmc   +1 more source