Tumor‐Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion
This study identifies Globo H ceramide (GHCer) as a novel immune checkpoint molecule that suppresses the activation of conventional T lymphocytes while promoting the differentiation and function of regulatory T cells. The immunosuppressive effects of GHCer are mediated through the activation of the A2AR/cAMP/PKA pathway, which involves its interactions
Jing‐Yan Cheng+13 more
wiley +1 more source
Complex papillary hyperplasia of the endometrium: an uncommon case report with cytopathological features and diagnostic implications. [PDF]
Wang R, Wu Y, Jia Z.
europepmc +1 more source
Automated 3D reconstruction of the normal and cirrhotic rat hepatic microcirculation using confocal microscopy: a feasibility study [PDF]
De Vos, Winnok+6 more
core +1 more source
Prevalence and clinicopathological features of human epidermal growth factor receptor-2-low breast cancers: A single-center experience. [PDF]
Cinar I.
europepmc +1 more source
Peromyscus spp. Deer Mice as Rodent Model of Acute Leptospirosis. [PDF]
Putz EJ+9 more
europepmc +1 more source
Aortic angiosarcoma leading to paraplegia: a case report. [PDF]
Li J, Sun J.
europepmc +1 more source
Impact of HER2 Status Assessed by Immunohistochemistry on Treatment Response in Patients with Metastatic Breast Cancer Receiving Trastuzumab Emtansine. [PDF]
Oksuz S+9 more
europepmc +1 more source