ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin [PDF]
Objective: In this research, we explored the molecular mechanism of proteinuria in glomerulosclerosis rats and the protective effects of ATRA. Methods: This research set up three groups: SHO group, GS group, and ATRA group (15 mg/(kg d), Sigma, St. Louis,
Lei Zhang +4 more
doaj +3 more sources
Concomitant loss of p120-catenin and β-catenin membrane expression and oral carcinoma progression with E-cadherin reduction. [PDF]
The binding of p120-catenin and β-catenin to the cytoplasmic domain of E-cadherin establishes epithelial cell-cell adhesion. Reduction and loss of catenin expression degrades E-cadherin-mediated carcinoma cell-cell adhesion and causes carcinomas to ...
Kazunobu Sasaya +4 more
doaj +3 more sources
Potential role of sugar transporters in cancer and their relationship with anticancer therapy. [PDF]
Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. Cancer cells are well known to display an enhanced sugar uptake and consumption.
Calvo MB +4 more
europepmc +2 more sources
Primary lymphomas arising in the large intestine are less frequent than either gastric or small bowel lymphomas. Primary colorectal lymphomas account for about 0.2% of all neoplasm. Mantle cell lymphoma in form of multiple lymphomatous polyposis is less
Kirti M Rathod +3 more
doaj +1 more source
THE PROFILE OF MATRIX METALLOPROTEINASE-9 IN RELATION TO COILING INDEX OF HUMAN UMBILICAL CORD
Background: Fetal blood flow through the umbilical cord vessels associated with abnormal coiling of the cord can have serious deleterious effects on the health of the fetus and newborn.
Hiba A. Abdul Sattar, Hayder J. Mubarak
doaj +6 more sources
Vergleichende TP53 targeted next-generation Sequenzierung zur Unterscheidung von Metastasen und Zweittumoren der Lunge bei Patienten mit Plattenepithelkarzinomen des Kopf-Hals-Bereichs und synchronen / metachronen Plattenepithelkarzinomen der Lunge [PDF]
Head and neck squamous cell carcinoma (HNSCC) is a malignant epithelial disease arising from the mucosa of the upper aerodigestive tract. It is the 6th most common malignancy worldwide with approximately 650 000 new cases diagnosed each year. In patients
Daher, Tamás
core +1 more source
CHYS inhibits renal fibrosis in diabetic rats.
Immunohitochemistry and quantitative analysis (A), Western blots and quantitative analysis (B), Real-time PCR for Collegen IV (C), collagen I (D) and fibronectin (E) expression, respectively.
Hao Jun Zhang (539315) +7 more
core +1 more source
THE EFFECTS OF ALLOGENEIC MSC ADMINISTRATION ON ATHEROSCLEROTIC VESSEL WALL (EXPERIMENTAL STUDY OF TGF-β1, IL-1α, AND IL-6 ON ATHEROSCLEROTIC SPRAGUE DAWLEY RATS) [PDF]
Background: Atherosclerosis is the leading cause of morbidity and mortality in the world. Mesenchymal stem cells (MSCs) are implicated in a variety of physiological and pathological processes.
Taufiq, Fikri
core +1 more source
By using a kinetic cadmium-reduction method for determination of inorganic nitrite and using immunohitochemistry method for observation of NOS immunoactivity in rat brain, we surveyed changes of inorganic nitrite and NOS immunoactivity in middle ...
施静 +4 more
doaj +2 more sources
Solid tumors contain heterogeneous cellular subpopulation due to a limit supply of oxygen, nutrients and wastes. This microenvironment affects local cell growth, survival and overall therapeutic efficacy.
Maria A. Jasnis +5 more
core +1 more source

