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Immunoinformatics and Epitope Prediction [PDF]
, 2020 With advancements in sequencing technologies, vast amount of experimental data has accumulated. Due to rapid progress in the development of bioinformatics tools and the accumulation of data, immunoinformatics or computational immunology emerged as a special branch of bioinformatics which utilizes bioinformatics approaches for understanding and ...
Jayashree Ramana, Kusum Mehla
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The immunoinformatics of cancer immunotherapy
Tissue Antigens, 2007AbstractWe review here the developments in the field of immunoinformatics and their present and potential applications to the immunotherapeutic treatment of cancer. Antigen presentation plays a central role in the immune response, and as a result in immunotherapeutic methods such as adoptive T‐cell transfer and antitumor vaccination.
David S. DeLuca, Rainer Blasczyk
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Vaccine Design and Immunoinformatics
2021The emanation use of vaccines has shown tremendous applications of computational algorithms that can be used for amelioration of health globally. Vaccine Research has become a center area of research that embarks its applications to save several lives, reduced cost of treatment, and potential inhibitor of infectious diseases.
Fariya Khan, Ajay Kumar
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Vaccines and Immunoinformatics for Vaccine Design
2022The host immune system recognizes and responds to the selective antigens or epitopes (immunome) of the intruding pathogen over an entire organism. The immune response so generated is ample to confer the desired immunity and protection to the host. This led to the conception of immunome-derived vaccines that exploit selective genome-derived antigens or ...
Shikha, Joon +2 more
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Putting immunoinformatics to the test
Nature Biotechnology, 2006A consensus epitope prediction approach identifies the epitopes responsible for 95% of the murine T-cell response to vaccinia virus.
Leonard Moise, Anne S. De Groot
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Immunoinformatic Identification of Potential Epitopes
2020Immunoinformatic plays a pivotal role in vaccine design and development. While traditional methods are exclusively depended on immunological experiments, they are less effective, relatively expensive, and time-consuming. However, recent advances in the field of immunoinformatics have provided innovative tools for the rational design of vaccine ...
Bhrugu Yagnik +3 more
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Immunoinformatics: A Brief Review
2014A large volume of data relevant to immunology research has accumulated due to sequencing of genomes of the human and other model organisms. At the same time, huge amounts of clinical and epidemiologic data are being deposited in various scientific literature and clinical records.
Rajat K. De, Namrata Tomar
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FROM IMMUNOINFORMATICS TO IMMUNOMICS
Journal of Bioinformatics and Computational Biology, 2003The immune system comprises a complex network of organs, specialized tissues, cells, and molecules. Its main function is to protect the organism from external and internal challenges and provides the interface between the organism and its environment. Foreign agents such as viruses, bacteria, fungi, or parasites may cause infection and disease. Foreign
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Immunoinformatics in Plant–Fungal Disease Management
2021It is estimated that by 2050 the world population will be ~10 billion. Ever-increasing population growth foists stress to the available lands and crops. Apart from postharvest losses, insects, pests, weeds, and the fungal pathogens cause huge economic losses to both agricultural and horticultural crops.
Sonika Nehra +3 more
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Immunoinformatics Vaccine Design for Zika Virus
2023Zika virus (ZIKV) is an emerging virus from the Flaviviridae family and Flavivirus genus that has caused important outbreaks around the world. ZIKV infection is associated with severe neuropathology in newborns and adults. Until now, there is no licensed vaccine available for ZIKV infection.
Ana Clara, Antonelli +2 more
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