Results 221 to 230 of about 169,700 (260)
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Immunomodulatory therapy for inflammatory bowel disease
Journal of Gastroenterology, 2004Patients with inflammatory bowel disease (IBD) have intestinal and extraintestinal symptoms that can greatly impair their quality of life. They must rely on multiple medications with aminosalicylates, corticosteroids, and purine analogues to control these symptoms.
Kazuo, Kusugami +5 more
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Future directions in immunomodulatory therapy
Medical Oncology, 2009The role of immunomodulatory-based therapy with thalidomide or lenalidomide is clearly established in the management of patients with myeloma in all phases of their disease. Recent preclinical and clinical works have demonstrated that in addition to combination therapy with dexamethasone, there is significant activity when combined with the proteasome ...
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Recent developments in immunomodulatory therapy
Journal of Allergy and Clinical Immunology, 1985The remarkable gains in basic immunologic knowledge have outpaced improvements in available agents or techniques that can be used to clinically modify the immune response. Many biologic and synthetic immunomodifiers, adjuvants, and drugs with both specific and/or nonspecific effects on immunity have been investigated.
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Immunomodulatory Therapies: Challenges of Individualized Therapy Strategies
2007"Individualized therapy strategies" involve strategies that allow treatment to be guided by patient-specific conditions. For this, robust biomarkers are needed. Examples of biomarker-guided therapies already in use are the treatment of insulin-dependent diabetes (biomarker: blood glucose level) or the treatment of hypertension (biomarker: blood ...
H D, Volk +5 more
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Immunomodulatory Therapies for Renal Cell Carcinoma
Protein & Peptide Letters, 2018Renal Cell Carcinoma (RCC) is the most common tumor originating from the kidneys. In comparison to other solid tumors, RCC is poorly sensitive to conventional therapeutic modalities. As such, metastatic RCC (mRCC) continues to be associated with high rates of morbidity and mortality. Targeted agents have shown remarkable progress in RCC management with
Min, Liu +8 more
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Thalidomide and immunomodulatory drugs as cancer therapy
Current Opinion in Oncology, 2002The demonstration of increased angiogenesis in cancer pathogenesis prompted the use of thalidomide in both solid tumors and hematologic malignancies. Its broad spectrum of actions besides its antiangiogenic potential, specifically, its immunomodulatory properties, antiinflammatory actions, and direct effect on tumor cells and their microenvironment ...
Noopur, Raje, Kenneth C, Anderson
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The immunomodulatory role of probiotics in allergy therapy
Journal of Cellular Physiology, 2018AbstractThe increased incidence of allergic disorders may be the result of a relative fall in microbial induction in the intestinal immune system during infancy and early childhood. Probiotics have recently been proposed as viable microorganisms for the prevention and treatment of specific allergic diseases. Different mechanisms have been considered for
Jafar Hajavi +9 more
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Principles of Immunomodulatory Therapy
1994This chapter concerns the principles of immunomodulatory therapy for use in the neurologic intensive care unit (ICU). These principles, which are derived from those generally used for patients receiving immunomodulatory therapy, are particularly important in the ICU.
David R. Cornblath +2 more
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Vaccines and Immunomodulatory Therapies for Food Allergy
Current Allergy and Asthma Reports, 2011The apparent increase in food allergy prevalence has led to a surge in the amount of clinical and basic science research dedicated to the field. At the current time, allergen avoidance remains the cornerstone of treatment; however, recent clinical trials investigating various forms of immunotherapy have opened doors to the possible future application ...
Jay A, Lieberman, Anna, Nowak-Węgrzyn
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Immunomodulatory Therapies in Neurologic Critical Care
Neurocritical Care, 2009Neurologic disorders with autoimmune dysregulation are commonly encountered in the critical care setting. Frequently encountered diseases include Guillain-Barré syndrome (GBS), myasthenia gravis, multiple sclerosis, acute demyelinating encephalomyelitis, and encephalitides. Immunomodulatory therapies, including high-dose corticosteroids, plasmapheresis,
Logan M, McDaneld +3 more
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