Results 191 to 200 of about 174,772 (308)

Engineering Bacteria as Living Therapeutics in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen   +6 more
wiley   +1 more source

Impact of steroid-sparing immunosuppressive agents on tumor outcome in the context of cancer immunotherapy with highlight on melanoma: a systematic literature review and meta-analysis. [PDF]

open access: yesFront Immunol
Strouse J   +12 more
europepmc   +1 more source

Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Targeted FABP5 co‐delivery nanoparticles amplify RFA‐induced ferroptosis and intratumoral immune rewiring via STING/TBK1 pathway activation in HCC. The pH‐responsive lipid nanoshell was integrated with cyclic RGD peptide (cRGD) and red blood cell membrane (RBCM), and encapsulated with superparamagnetic iron oxide (SPIO) and sgFABP5 to construct FS@RBCM/
Bufu Tang   +16 more
wiley   +1 more source

Long-term islet graft survival in streptozotocin- and autoimmune-induced diabetes models by immunosuppressive and potential insulinotropic agent fty720

open access: bronze, 2002
Fumin Fu   +9 more
openalex   +1 more source

Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor

open access: yesAdvanced Science, EarlyView.
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao   +10 more
wiley   +1 more source

Long-term outcome of autologous haematopoietic stem cell transplantation in patients with systemic sclerosis: a comparison with patients treated with rituximab and with traditional immunosuppressive agents. [PDF]

open access: yesArthritis Res Ther
Del Papa N   +13 more
europepmc   +1 more source

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