Results 191 to 200 of about 203,270 (263)

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

Immunosuppressive agents: Role in corneal graft rejection

Journal of Clinical Ophthalmology and Research, 2013
Rajesh Sinha, Sana Iliyas Tinwala, Himanshu Shekhar, Jeewan S Titiyal   +3 more
doaj  

Impact of varied immunosuppressive agents and post-transplant diabetes mellitus on prognosis among diverse transplant recipients (experimental studies). [PDF]

Int J Surg
Liu Y, Zheng J, He Q, Zhang H, Wen P, Wen P, Ge J, Yang Y, Zhang T, Wang R.   +9 more
europepmc   +1 more source

iPRISM: Intelligent Predicting Response to Cancer Immunotherapy through Systematic Modeling

Advanced Intelligent Systems, EarlyView.
The Intelligent Predicting Response to cancer Immunotherapy through Systematic Modeling (iPRISM) model uses data from genes and immune responses to predict how well cancer patients will respond to immunotherapy. Tested on multiple cancer types, iPRISM shows higher accuracy compared to existing methods.
Yinchun Su, Siyuan Li, Qian Wang, Bingyue Pan, Jiyin Lai, Guangyou Wang, Junwei Han, Qingfei Kong   +7 more
wiley   +1 more source

TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah, Daniel A. Arber, Devendra K. Hiwase   +2 more
wiley   +1 more source

Pharmacological immunosuppressive agents

, 1981
openaire   +2 more sources

Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives

American Journal of Hematology, EarlyView.
ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

Angewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu, Xiaocao Ma, Jingguo Wang, Tiantian Chen, Jiahui Yang, Yan Liu, Zhun Lin, Minhao Wu, Tony Y. Hu, Yuanqing Zhang   +9 more
wiley   +2 more sources

Immunosuppressive agents for treating IgA nephropathy. [PDF]

Cochrane Database Syst Rev, 2020
Natale P, Palmer SC, Ruospo M, Saglimbene VM, Craig JC, Vecchio M, Samuels JA, Molony DA, Schena FP, Strippoli GF.   +9 more
europepmc   +1 more source

Facile Access to Piezoelectric Polyamides by Polyamidation of Carboxylic Acids and Ynamides for Potent Tumor Immunotherapy

Angewandte Chemie, EarlyView.
We establish a simple polyamidation of carboxylic acids and ynamides to synthesize versatile piezoelectric polyamides, with the merits of 100% atom economy, no waste generation, and additive‐free as well as catalyst‐free system. Tetraphenylethene containing polyamides can generate reactive oxygen species and elicit robust immunogenic cell death ...
Xingguang Li, Ruiqi Yan, Mei Tan, Ryan T. K. Kwok, Jianwei Sun, Huijing Xiang, Xiang Ma, Jacky W. Y. Lam, Ben Zhong Tang   +8 more
wiley   +2 more sources