Results 221 to 230 of about 165,216 (289)

COVID-19 in rheumatic disease patients on immunosuppressive agents. [PDF]

Semin Arthritis Rheum, 2020
Sharmeen S, Elghawy A, Zarlasht F, Yao Q.   +3 more
europepmc   +1 more source

Therapeutic use of glucocorticoids and immunosuppressive agents

, 2005
Leposava Grbović, Miroslav Radenković
openalex   +2 more sources

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

Advanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin, Jianyi Ding, Jie Liu, Haoran Hu, Yashi Zhu, Meiqin Yang, Huijuan Zhou, Baoyou Huang, Tiefeng Huang, Mengjie Li, Yinyan He, Ang Li, Lingfei Han   +12 more
wiley   +1 more source

Influence of immunosuppressive agents on magnesium (Mg) metabolism after allogeneic hematopoietic stem cell transplantation (HSCT): Comparison between cyclosporine a (CSA) and tacrolimus

, 2005
Yoshinobu Aisa, Takehiko Mori, Takayuki Shimizu, Rie Yamazaki, Akiko Yamane, Akiko Adachi, Akira Yokoyama, Tomonori Nakazato, Y. Ikeda, Shinichiro Okamoto   +9 more
openalex   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source

A Case of Canine Protein-losing Enteropathy Treated with Immunosuppressive Agents

, 2005
Masashi Yuki, Noriko Sugimoto, Takashi Higuchi, Kuniaki Takahashi, Hiromi OTSUKA, Kiyomi Suzuki   +5 more
openalex   +2 more sources

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

Advanced Science, EarlyView.
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei, Wenbin Dai, Jinchao Zhao, Angfeng Jiang, Haisheng Peng, Qiao Jin, Xiaojing Li, Zhe Tang   +7 more
wiley   +1 more source

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

Drug Interactions between Antimicrobial and Immunosuppressive Agents in Solid Organ Transplant Recipients.

Indian J Crit Care Med, 2021
Bhagat V, Pandit RA, Ambapurkar S, Sengar M, Kulkarni AP.   +4 more
europepmc   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source