Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai+5 more
wiley +1 more source
Immunosuppressive agents for frequently relapsing/steroid-dependent nephrotic syndrome in children: a systematic review and network meta-analysis. [PDF]
Zhu Y, Chen J, Zhang Y, Wang X, Wang J.
europepmc +1 more source
Chiral Vinylphosphonate and Phosphonate Analogues of the Immunosuppressive Agent FTY720 [PDF]
Xuequan Lu+6 more
openalex +1 more source
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang+6 more
wiley +1 more source
Immunosuppressive agents: Role in corneal graft rejection
Rajesh Sinha+3 more
doaj
Nintedanib combined with immunosuppressive agents improves forced vital capacity in connective tissue disease-associated PF-ILD: a single-center study. [PDF]
Ushio Y+13 more
europepmc +1 more source
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen+5 more
wiley +1 more source
Antibody-based immunosuppressive agents for corneal transplantation [PDF]
Michael Thiel+3 more
openalex +1 more source
Impact of varied immunosuppressive agents and post-transplant diabetes mellitus on prognosis among diverse transplant recipients (experimental studies). [PDF]
Liu Y+9 more
europepmc +1 more source