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New agents for immunosuppression
Best Practice & Research Clinical Gastroenterology, 2021The human abdomen harbors organs that the host's immune system can attack easily. This immunological storm front leads to diseases like Crohn's Disease, Ulcerative Colitis or Autoimmune Hepatitis. Serious symptoms like pain, diarrhea, fatigue, or malnutrition accompany these diseases.
André Jefremow, Markus F. Neurath
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Surgical Clinics of North America, 1994
The present success of organ transplantation is largely due to advances in immunosuppressive therapy. Progress has been made from a cytotoxic strategy associated with a high morbidity rate to a strategy that seeks to alter the activity of cells that regulate the immune response, in order to selectively dampen antidonor responses.
B D, Kahan, R, Ghobrial
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The present success of organ transplantation is largely due to advances in immunosuppressive therapy. Progress has been made from a cytotoxic strategy associated with a high morbidity rate to a strategy that seeks to alter the activity of cells that regulate the immune response, in order to selectively dampen antidonor responses.
B D, Kahan, R, Ghobrial
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Gastroenterology Clinics of North America, 1993
In summary, many new modalities of immunosuppression after transplantation are being investigated (Fig. 1). These approaches include various new drugs or monoclonal antibodies that target different cell subsets, cellular activation pathways, cellular effector function or mediators (such as cytokines) of effector function, ligands that stabilize ...
G L, Bumgardner, J P, Roberts
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In summary, many new modalities of immunosuppression after transplantation are being investigated (Fig. 1). These approaches include various new drugs or monoclonal antibodies that target different cell subsets, cellular activation pathways, cellular effector function or mediators (such as cytokines) of effector function, ligands that stabilize ...
G L, Bumgardner, J P, Roberts
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Immunosuppressive Agents in Dermatology
Dermatologic Clinics, 1993Azathioprine, cyclophosphamide, and cyclosporine are immunosuppressive agents commonly used by dermatologists. Azathioprine has a good safety profile and is preferred by most dermatologists for the treatment of bullous pemphigoid, cutaneous vasculitides, chronic eczematous dermatitides, and cutaneous manifestations of connective tissue diseases.
V C, Ho, D M, Zloty
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IMMUNOSUPPRESSIVE AGENTS IN DERMATOLOGY
Dermatologic Clinics, 1998Azathioprine, cyclophosphamide, methotrexate, and cyclosporine are the immunosuppressive agents most commonly used by dermatologists. Azathioprine has a relatively good safety profile and is therefore often preferred for the treatment of chronic eczematous dermatitides and bullous disorders.
Vincent C. Ho, Jan P. Dutz
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Immunosuppressive agents for myasthenia gravis
Cochrane Database of Systematic Reviews, 2005The benefits of different immunosuppressants for myasthenia gravis (MG) are unclear.Assessment of immunosuppressant drug efficacy in MG.We searched the Cochrane Neuromuscular Disease Group Trials Register, MEDLINE (from January 1966 to July 2007), EMBASE (from January 1980 to July 2007), review and trial bibliographies and contacted trial authors.Types
Tarek Sharshar +2 more
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Immunosuppressive agents and asthma
Clinical Reviews in Allergy, 1994One of the goals of asthma therapy is to maintain control of symptoms without producing unwanted effects from asthma medications. Corticosteroids are the mainstay for intractable chronic asthma, but their long-term use in high doses is limited by the risk of significant adverse effects.
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Glucocorticosteroids as immunosuppressive agents
Seminars in Veterinary Medicine and Surgery: Small Animal, 1997When administered at pharmacological dosages, glucocorticosteroid hormones alter leukocyte kinetics, phagocytic cell function, cell-mediated immunity, and, to a lesser extent, humoral immunity. These properties are used to advantage in the treatment of immunologically mediated disease.
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Dermatologic Therapy With Immunosuppressive Agents
Postgraduate Medicine, 1975The use of powerful immunosuppressive agents such as methotrexate, cyclophosphamide, and azathioprine in the treatment of serious skin diseases is a relatively recent development whose efficacy is borne out in many studies. Using an immunosuppressant often makes possible an appreciable reduction in dosage of steroid necessary to control disease and, in
Robert I. Rudolph, James J. Leyden
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Bacterial endotoxins as immunosuppressive agents
Experientia, 1971Der Adjuvanseffekt von bakteriellem Endotoxin gegenuber Schaferythrocyten war nicht nachweisbar, wenn Mause vor der primaren antigenen Stimulierung 9 Tage lang eine tagliche Injektion von 20 µg Endotoxin erhielten. Andererseits wurde unter diesen Bedingungen eine Primarreaktion gefunden, wie sie nach alleiniger Injektion des Erythrocytenantigens zur ...
H. Fresenius, M. Angerer, H. Finger
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