Results 261 to 270 of about 3,627,754 (377)
Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin +8 more
wiley +1 more source
Nintedanib combined with immunosuppressive agents improves forced vital capacity in connective tissue disease-associated PF-ILD: a single-center study. [PDF]
Ushio Y +13 more
europepmc +1 more source
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang +9 more
wiley +1 more source
A cold atmospheric plasma‐activated in situ hydrogel (CAPgel/IL2) delivers reactive oxygen species and interleukin‐2 to modulate the hair follicle immune microenvironment, enhancing regulatory T‐cell expansion, dermal papilla cell proliferation, and the telogen‐to‐anagen transition for robust hair regeneration.
Jung Suk Kim +7 more
wiley +1 more source
E, Czarnecka, J, Staszewski
openaire +3 more sources
Impact of varied immunosuppressive agents and post-transplant diabetes mellitus on prognosis among diverse transplant recipients (experimental studies). [PDF]
Liu Y +9 more
europepmc +1 more source
A modular nanoplatform capable of sequentially reprogramming tumor microenvironment via cascade actions and responsive therapeutic functions is reported for breast cancer therapy. Via a dual‐targeting mechanism and responsive PD‐L1 antibody release, this nanoplatform enables amplified sonodynamic‐chemodynamic therapy and elicits robust immune response ...
Yang Yu +5 more
wiley +1 more source

