Results 291 to 300 of about 254,031 (357)

State of immunosuppressive agents in organ transplantation [PDF]

, 1992
Fung, JJ, Pinna, A, Selby, RR, Starzl, TE, Thomson, AW   +4 more
core  

Radiomics‐Based Unsupervised Clustering Identifies Subtypes Associated With Prognosis and Immune Microenvironment in Clear Cell Renal Cell Carcinoma: A Multicenter Study

Advanced Science, EarlyView.
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo, Bingxin Gong, Yi Li, Jie Lou, Shuai Shan, Xiaodong Zhang, Qiang Lu, Dongyong Zhu, Qing Sun, Lianwei Miao, Yuanxi Li, Yu‐Dong Zhang, Wei Tan, Lian Yang, Chuansheng Zheng   +14 more
wiley   +1 more source

Organ Transplantation: The Ethics of Consequences [PDF]

, 2002
Weringer, Elora J.
core   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

Advanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen, Hsien‐Chung Chen, Chien‐Liang Lin, Amandeep Thakur, Raphael Onuku, I‐Chung Chen, Hao‐Yi Li, Kwang‐Yu Chang, Jian‐Ying Chuang, Wen‐Bin Yang, Hong‐Yi Lin, Yi‐Ru Shen, Jing‐Ping Liou, Wen‐Chang Chang, Tsung‐I Hsu   +14 more
wiley   +1 more source

Liver homotransplantation [PDF]

, 1986
Iwatsuki, S, Shaw, BW, Starzl, TE
core  

Tacrolimus (FK506) and therapy of human autoimmune disorders [PDF]

, 1996
Abu-Elmagd, K, Carroll, PB, Irish, W, McCauley, J, McMichael, J, Rilo, HR, Starzl, TE, Thomson, AW, Van Thiel, DH   +8 more
core  

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Immunosuppressive Agents

Annual Review of Pharmacology, 1972
Publisher Summary This chapter examines immunosuppressive agents for immunosuppressive effect. It discusses the effect of irradiation on immune response. Irradiation is the least effective of all the immunosuppressive agents used in clinical practice. However, irradiation is used considerably in clinical practice.
A, Gerebtzoff, P H, Lambert, P A, Miescher   +2 more
openaire   +4 more sources

New agents for immunosuppression

Best Practice & Research Clinical Gastroenterology, 2021
The human abdomen harbors organs that the host's immune system can attack easily. This immunological storm front leads to diseases like Crohn's Disease, Ulcerative Colitis or Autoimmune Hepatitis. Serious symptoms like pain, diarrhea, fatigue, or malnutrition accompany these diseases.
André Jefremow, Markus F. Neurath
openaire   +2 more sources

Immunosuppressive Agents

Surgical Clinics of North America, 1994
The present success of organ transplantation is largely due to advances in immunosuppressive therapy. Progress has been made from a cytotoxic strategy associated with a high morbidity rate to a strategy that seeks to alter the activity of cells that regulate the immune response, in order to selectively dampen antidonor responses.
B D, Kahan, R, Ghobrial
openaire   +2 more sources