Results 101 to 110 of about 314,880 (255)

In vivo crosslinking and effective 2D enrichment for proteome wide interactome studies

Communications Chemistry
Cross-linking mass spectrometry has evolved as a powerful technique to study protein-protein interactions and to provide structural information. Low reaction efficiencies, and complex matrices lead to challenging system wide crosslink analysis.
Philipp Bräuer, Laszlo Tirian, Fränze Müller, Karl Mechtler, Manuel Matzinger   +4 more
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Mime-seq 2.0: a method to sequence microRNAs from specific mouse cell types

The EMBO Journal
Many microRNAs (miRNAs) are expressed with high spatiotemporal specificity during organismal development, with some being limited to rare cell types, often embedded in complex tissues.
Ariane Mandlbauer, Qiong Sun, Niko Popitsch, Tanja Schwickert, Miroslava Spanova, Jingkui Wang, Stefan L Ameres, Meinrad Busslinger, Luisa Cochella   +8 more
doaj   +1 more source

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

An exploratory taxonomic study of IMP Group conference papers

, 2002
The paper describes exploratory research into the nature of IMP conference papers with particular focus on content. A qualitative analysis of the proceedings of the 16th annual IMP conference is presented. The results provide insights into the diversity
Bettany, S., Easton, G., Zolkiewski, J.
core  

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

La voz del pueblo (Gerona. 1893)

, 1893
Título tomado de la cabeceraA partir del Año II, n. 40 (31 marzo 1894) subtít.: semanario republicanoCopia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 2003Descripción basada en: Año I, n. 2 (jun.
Imprenta Guttenberg (Gerona) (imp.), Imprenta de La voz del pueblo (Gerona) (imp.)   +1 more
core   +1 more source

Functional and structural analyses of IMP-27 metallo-β-lactamase: evolution of IMP-type enzymes to overcome Zn(II) deprivation

Microbiology Spectrum
IMP-type metallo-β-lactamases are di-Zn(II) enzymes that can inactivate a wide range of bicyclic β-lactam agents used in clinical practice. IMP-27 shares 82% amino acid sequence identity with IMP-1, the first IMP-type enzyme identified.
Yoshiki Kato, Toshio Yamaguchi, Haruka Nakagawa-Kamura, Yoshikazu Ishii, Akiko Shimizu-Ibuka   +4 more
doaj   +1 more source

Imp-β2 is involved in moving Gli2 into the cilium.

, 2016
(A) NIH/3T3 Flp-In cells expressing GFP-Gli2 were transfected with either myc-MBP-M9M or myc-MBP as control, stimulated with SAG and Gli2 ciliary localization was analysed in transfected cells.
Belén Torrado (3140616), Martín Graña (420), José L. Badano (3140619), Florencia Irigoín (3140622)   +3 more
core   +1 more source

Further Evidences for the Sulfur Spillover on Carbon: Thermodynamic Aspects and Effects on Li‐S Solid‐State Batteries

Advanced Science, EarlyView.
ABSTRACT This study investigates sulfur spillover, the spontaneous and rapid spread of sulfur over carbon surfaces at ambient temperature. The process is studied by small‐angle X‐ray scattering (SAXS), X‐ray radiography, and microcalorimetry from which a number of physicochemical properties are derived.
Francesco Piccolo, Anka Berger, Sebastian Risse, Román Healy Corominas, Wilhelm Erth, Florian Fuchs, Jesus Andrade, Jörg Schuster, Marc Armbrüster, Philipp Adelhelm   +9 more
wiley   +1 more source