Results 101 to 110 of about 13,555,111 (308)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
BMJ OpenObjectives The primary objective was to assess the acceptability of a savings intervention in which female sex workers (FSW) would save part of their earnings and call back (withdraw) when faced with a financial need that could force them into HIV risk ...
Harsha Thirumurthy +10 more
doaj +1 more source
Theory of Change (ToC): A Method for Impact Planning and Assessment
Theory of Change (ToC) is a formative, process-based evaluation method that is most often used to inform or improve project planning. This is a description of the framework based on scientific literature, in which you can learn about Theory of Change ...
Evaluating Societal Impact
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Unraveling Concussion Impact by Impact
Journal of Eye Movement Research, 2019 Keynote at the 20th European Conference on Eye Movement Research (ECEM) in Alicante, 20.8.2019.
openaire +4 more sources
The Impact of Impact Factors [PDF]
Stroke, 2001 When impact factors rise, editors editorialize. When they fall, editors fall silent. The impact factor of Stroke has risen from 5.53 in 1999 to 6.008 in 2000. It is time to editorialize. These statistics reaffirm Stroke as the leading publication in the field, place it among the top 3 clinical neurological journals along with Brain and the Annals of ...
openaire +1 more source
Impact behaviour of flax/epoxy composite plates [PDF]
, 2015 This paper presents an experimental investigation of the impact behaviour of flax/epoxy composite plates submitted to low-velocity transverse impact.
GNING, Papa-Birame +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The impact of the impact factor [PDF]
The EMBO Reports, 2000 As a new journal yet unbranded by an impact factor (IF), we can address this important element of science without suffering either the anguish of those journals that languor in the lower divisions or the insouciance of those with double digit IFs. This number, as abstract as it is, has become the pervasive arbiter of scientific careers for those who ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source