Results 201 to 210 of about 30,396,780 (392)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Exploring the Impact of Motivation on Language Learning and Student Engagement
, 2023 Carlo Vinci L. Arcipe, Jerlyn G. Balones
openalex +2 more sources
Hedging our bet on forest permanence for the economic viability of climate targets
Nature CommunicationsAchieving the Paris Agreement’s CO2 emission reduction goals heavily relies on enhancing carbon storage and sequestration in forests globally. Yet, the increasing vulnerability of carbon stored in forests to both climate change and human intervention is ...
Michael G. Windisch +10 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Impact of the CYP2C19 genotype on voriconazole exposure in adults with invasive fungal infections
, 2017 Issam S. Hamadeh +11 more
openalex +1 more source
Assessing the impact of the EU ETS using firm level data [PDF]
This paper investigates the impact of the European Unionâ??s Emission Trading System (EU ETS) at a firm level. Using panel data on the emissions and performance of more than 2000 European firms from 2005 to 2008, we are able to analyse the effectiveness ...
Anta Ndoye, Georg Zachmann, Jan Abrell
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Energetic consistency conditions for standard impacts
, 2012 Christoph Glocker
openalex +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source