Results 311 to 320 of about 30,396,780 (392)
Measuring impact and impacting practice.
openaire +2 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A systematic review and meta-synthesis of qualitative studies of alopecia: Managing identity and appearance changes. [PDF]
Hurrell Z +3 more
europepmc +1 more source
The Impact of Cavity Preparation Methods on Children's Dental Anxiety
Andreea Igna +6 more
openalex +2 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Young People's Subjective Wellbeing in the Wake of the COVID-19 Pandemic: Evidence from a Representative Cohort Study in England. [PDF]
Anders J, Holt-White E.
europepmc +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
A comparative multi-objective investigation for metallic and non-metallic materials on the erosion resistance of wind turbine blade with performance evaluation. [PDF]
Abou Taleb ASA, Abdelgaliel IH, Aly MF.
europepmc +1 more source

