Results 31 to 40 of about 5,507,035 (268)

Midwestern specialty crop impacts on the environment and health: a scoping review

Agriculture & Food Security
Introduction The United States food system mainly relies on monoculture farming, leading to negative impacts on human and environmental health. Transitioning to specialty crop production (fruits, vegetables, and tree nuts) could alleviate challenges. The
Laura E. Balis, Emily Shaw, Whitney Fung Uy, Katie Nelson, Maryan Isack, Laura Flournoy, Daniele Vest, Jessie Deelo, Amy L. Yaroch   +8 more
doaj   +1 more source

A new frontier in treatment of advanced melanoma: Redefining clinical management in the era of immune checkpoint inhibitors

Human Vaccines & Immunotherapeutics, 2017
Immune checkpoint inhibitors have revolutionized treatment of advanced cutaneous melanoma. This group of novel therapeutic agents differs from other systemic treatments and has necessitated a new approach for several fundamental aspects of clinical ...
Oren Levine, Tahira Devji, Feng Xie
doaj   +1 more source

Inequalities in oral health: The economic burden of dental caries

International Dental Journal, 2023
Aim or Purpose: This study aimed to: determine the lifetime costs of preventing and managing of dental caries in five countries (Brazil, Germany, Indonesia, Italy, UK), and assess the impact on these costs from levelling up prevention and management ...
Dr Gerard Dunleavy, Prof Moritz Kebschull, Prof Nigel Pitts, Prof Iain Chapple, Neeladri Verma, Shivangi Jain, Joao Hofmeister, Kati Chilikova, Rob Cook, Prof Nicola West   +9 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

2040 greenhouse gas reduction targets and energy transitions in line with the EU Green Deal

Nature Communications
The European Green Deal aims to guide the European Union towards achieving net-zero greenhouse gas emissions by implementing a comprehensive set of policy initiatives and legislation.
Renato Rodrigues, Robert Pietzcker, Joanna Sitarz, Anne Merfort, Robin Hasse, Johanna Hoppe, Michaja Pehl, Ahmad Murtaza Ershad, Jarusch Muessel, Felix Schreyer, Lavinia Baumstark, Gunnar Luderer   +11 more
doaj   +1 more source

The Power of Advocacy: Advancing Vision for Everyone to Meet the Sustainable Development Goals

International Journal of Public Health, 2022
Advocacy is instrumental to achieving significant policy change for vision. Global advocacy efforts over the past decades enabled recognition of vision as a major public health, human rights, and development issue.
Eva Lazuka-Nicoulaud, Kovin Naidoo, Kristan Gross, Judith Marcano Williams, Andrea Kirsten-Coleman   +4 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The impact of impact [PDF]

The Biochemist, 2010
The proposed introduction of impact into research funding assessments has been controversial. The current proposals for the new quality-related research (QR) framework contribute to a very tense environment which also includes looming cuts to higher education budgets.
openaire   +1 more source

Limited progress in global reduction of vulnerability to flood impacts over the past two decades

Communications Earth & Environment
Global flood impacts have risen in recent decades. While increasing exposure was the dominant driver of surging impacts, counteracting vulnerability reductions have been detected, but were too weak to reverse this trend. To assess the ongoing progress on
Inga J. Sauer, Benedikt Mester, Katja Frieler, Sandra Zimmermann, Jacob Schewe, Christian Otto   +5 more
doaj   +1 more source