Optimizing Budget Allocation for Digital Health Investments Using Metaheuristic Algorithms: A Cost-Impact Analysis for Public Health Systems. [PDF]
Dayi F +4 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Causal impact analysis for app releases in google play
William J. Martin +2 more
semanticscholar +1 more source
Bioengineering approaches to dynamic impact analysis for cranial fracture interpretation in arcaheology. [PDF]
Rodríguez-Iglesias D +4 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Traffic operational evaluation of traffic impact analysis (TIA) case sites. [PDF]
2009 - 09This report summarizes traffic operational evaluation of six select traffic impact analysis (TIA) case sites and the effectiveness of forecasting methods used in TIA studies.
Pulugurtha, Srinivas S. +1 more
core
An Industrial Survey of Safety Evidence Change Impact Analysis Practice
J. Vara +3 more
semanticscholar +1 more source
NetZero deep brain stimulation: A carbon footprint minimisation audit and environmental impact analysis. [PDF]
Scott T, Pereira EA, Hart MG.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source

