Results 201 to 210 of about 37,251,550 (358)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Causal impact analysis for app releases in google play

open access: yesSIGSOFT FSE, 2016
William J. Martin   +2 more
semanticscholar   +1 more source

Global Challenges: Climate Change

open access: yesGlobal Challenges, 2017
Georg Feulner
doaj   +1 more source

Bioengineering approaches to dynamic impact analysis for cranial fracture interpretation in arcaheology. [PDF]

open access: yesSci Rep
Rodríguez-Iglesias D   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Traffic operational evaluation of traffic impact analysis (TIA) case sites. [PDF]

open access: yes
2009 - 09This report summarizes traffic operational evaluation of six select traffic impact analysis (TIA) case sites and the effectiveness of forecasting methods used in TIA studies.
Pulugurtha, Srinivas S.   +1 more
core  

An Industrial Survey of Safety Evidence Change Impact Analysis Practice

open access: yesIEEE Transactions on Software Engineering, 2016
J. Vara   +3 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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