Results 261 to 270 of about 42,261,326 (330)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Nationwide Hypothermic Machine Perfusion for ECD and DCD Kidney Transplantation in Belgium: One-Year Outcomes and Impact on Transplant Rates and Budget Impact Analysis. [PDF]

Transpl Int
Darius T, Jochmans I, Foguenne M, Hoste E, Randon C, Bracke B, Roeyen G, Gilbo N, Weekers L, Jacobs-Tulleneers-Thevissen D, Wissing KM, Bogaerts T, Mikhalski D, De Wilde JP, Daems J, Pirenne J.   +15 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Economic Evaluation and Budget Impact Analysis of Indocyanine Green Test for Preoperative Liver Function in Patients with Major Hepatectomy in Thailand. [PDF]

Adv Ther
Permsuwan U, Sriuttha P, Tovikkai C, Chotirosniramit A, Thepbunchonchai A, Junrungsee S, Lapisatepun W, Chaiyabutr K, Srisuk T, Dilokthornsakul P.   +9 more
europepmc   +1 more source

Impact analysis of tunnel crossing pile foundation at different angles. [PDF]

Sci Rep
Tian Z, Zhang Z, Zhang G, Shan X, Liu W.
europepmc   +1 more source

Surface Quality and Environmental Impact Analysis of Ball Burnishing on Al8090 Aluminum-Lithium Alloy. [PDF]

Materials (Basel)
Cagan SC.
europepmc   +1 more source

Impact analysis of expanding antibiotic use for treatment of uncomplicated appendicitis without appendicolith. [PDF]

J Comp Eff Res
Poehler D, Kirsch S, Dempsey M, Giombi K, Khavjou O.   +4 more
europepmc   +1 more source

Assessment of the Mechanical Properties of Soft Tissue Phantoms Using Impact Analysis. [PDF]

Sensors (Basel)
Bouffandeau A, Poudrel AS, Brossier C, Rosi G, Nguyen VH, Flouzat-Lachaniette CH, Meningaud JP, Haïat G.   +7 more
europepmc   +1 more source