Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Evaluation and optimization of municipal-level health impact assessment policies in China based on the PMC index model. [PDF]
Front Public HealthZhou Y, Cheng L, Zhu Y, Yuan J, Ma Y.
europepmc +1 more source
INTEGRATING HEALTH IMPACT ASSESSMENT INTO ENVIRONMENTAL IMPACT ASSESSMENT
SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings, 2013 openaire +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Ex post impact assessment of Marwa rehabilitation on irrigation performance under water scarcity in Egypt. [PDF]
Sci RepEmbaby M.
europepmc +1 more source
Impact assessment of telehealth medical nutrition therapy for managing cardiovascular disease risk in rural and remote NSW: the Healthy Rural Hearts study. [PDF]
Health Res Policy SystBudden KF +13 more
europepmc +1 more source
Innovative nursing training in prehospital trauma care: design and impact assessment using a dual-cabin ambulance simulator. [PDF]
BMC NursNazari P +5 more
europepmc +1 more source