Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
PCD Receives Highest 5-Year Journal Impact Factor in Its History: Celebrating and Building on 20 Years of Success With Release of 6 Collections in 2025. [PDF]
Jack L.
europepmc +1 more source
The Momentous 2023: Publication Frequency, Impact Factor, and IJPS Archival.
Kadam D.
europepmc +1 more source
Impact of Environmental & Psychological Factors on Driver’s Behavior and its Respective Effective Measures to be Taken in Terms of Improving Roadway Design and Policymaking [PDF]
Sumbul Mujeeb +5 more
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Editor's Note on Recent Journal Impact Factor of Cancer Research and Treatment. [PDF]
Ahn YC.
europepmc +1 more source
Journal Impact Factor for the Indian Journal of Plastic Surgery.
Kadam D.
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
2023 Journal Citation Report impact factor update and achievements for the Journal of Periodontal & Implant Science. [PDF]
Park JB +5 more
europepmc +1 more source

