Results 101 to 110 of about 1,388,210 (307)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Geometrically nonlinear analysis of the Apollo aft heat shield Final report, 1 Apr. 1966 - 15 Dec. 1966 [PDF]
Structural analysis of Apollo aft heat shield under water impact loading ...
Gallagher, R. H., Mallet, R. H.
core +1 more source
Strain localization analysis using a multiscale model [PDF]
, 2007 In order to analyze the formability of steels in sheet metal forming, a ductility loss criterion is coupled with a multiscale model. The behavior at the mesoscopic (grain) scale is modeled by a large strain micromechanical constitutive law, which is then
ABED-MERAIM, Farid +4 more
core +8 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Nanomaterials, 2018 The beetle elytra requires not only to be lightweight to make a beetle fly easily, but also to protect its body and hind-wing from outside damage. The honeycomb sandwich structure in the beetle elytra make it meet the above requirements.
Jianxun Du, Peng Hao
doaj +1 more source
Shock and Release Temperatures in Molybdenum
, 2007 Shock and release temperatures in Mo were calculated, taking account of heating from plastic flow predicted using the Steinberg-Guinan model. Plastic flow was calculated self-consistently with the shock jump conditions: this is necessary for a rigorous ...
A. Seifter +10 more
core +1 more source
Microstructure Controlled Shear Band Pattern Formation and Enhanced Plasticity of Bulk Metallic Glasses Containing in situ Formed Ductile Phase Dendrite Dispersions [PDF]
, 2000 Results are presented for a ductile metal reinforced bulk metallic glass matrix composite based on glass forming compositions in the Zr-Ti-Cu-Ni-Be system.
Hays, C. C., Johnson, W. L., Kim, C. P.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Applied Sciences, 2017 The behaviour of an asphalt concrete structure subjected to severe loading, such as blast and impact loadings, is becoming critical for safety and anti-terrorist reasons.
Jun Wu, Liang Li, Xiuli Du, Xuemei Liu
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source