Results 171 to 180 of about 1,388,210 (307)

Energy Evolution and Fine Structure Effects in Typical Rocks Subjected to Impact Loading. [PDF]

Materials (Basel)
Deng D, Liu G, Guo L, Li Y, Hua J.
europepmc   +1 more source

Damage evolution and constitutive model of the rock masses with non-penetrating cracks under repeated impact loading. [PDF]

PLoS One, 2023
Zhang J, Wu X.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Study on radial fracture mechanism of saturated granite subjected to coupled static-cyclic impact loading: An experimental investigation. [PDF]

PLoS One
Wang Y, Liu X, Xu Z, Tang H.
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Research on the tensile fracture mechanism of reinforced rubber concrete under impact loading conditions. [PDF]

Sci Rep
Zhu B, Ling R, Wu C.
europepmc   +1 more source

Influence of Interface on Mechanical Behavior of Al-B₄C/Al Laminated Composites under Quasi-Static and Impact Loading. [PDF]

Materials (Basel), 2023
Zhang R, Chao Z, Jiang L, Han H, Han B, Du S, Luo T, Chen G, Mei Y, Wu G.   +9 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Study on mechanical behavior and energy evolution of coal under different gas pressures under impact loading. [PDF]

Sci Prog
Dai L, Cheng X, Cao J, Mao L, Yang H, Li J, Li R.   +6 more
europepmc   +1 more source

Shock absorption capability of corrugated ring yield mount subjected to high impact loading. [PDF]

Heliyon, 2023
Khan S, Shahiq M, Iqbal MZ.
europepmc   +1 more source