Results 51 to 60 of about 1,388,210 (307)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Influence of muscle preactivation of the lower limb on impact dynamics in case of frontal collision
Accidentology or shock biomechanics are research domains mainly devoted to the development of safety conditions for the users of various transport modes in case of an accident. The objective of this study was to improve the knowledge of the biomechanical
Chavet, Pascale +3 more
core +4 more sources
Core crush criterion to determine the strength of sandwich composite structures subjected to compression after impact [PDF]
In this study a core crush criterion is proposed to determine the residual strength of impacted sandwich structures. The core of the sandwich is made of a Nomex Honeycomb core and the faces are laminated and remain thin.
Aminanda, Yulfian +3 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Mechanical safety of reinforced concrete frames under complex emergency actions
An approach to the calculation of the frame reinforced concrete structures taking into account the potential risk of financial losses in an emergency is proposed.
Anatoly Alekseytsev
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Electronic devices play an extremely important role in the aerospace field. Aluminum nitride (AlN) is a promising ceramic material for high-reliability electronic packaging structures that are subjected to impact loads during service.
Zhen Wang, Yan Liu
doaj +1 more source
A portable load cell for in-situ ore impact breakage testing [PDF]
This paper discusses the design and characterisation of a short, and hence portable impact load cell for in-situ quantification of ore breakage properties under impact loading conditions.
Banini, George, Bourgeois, Florent
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Cell wall material strain hardening on dynamic responses of closed-cell foams
The paper focuses on the effects of the cell wall material strain hardening on the mechanical behavior of closed-cell foams subjected to the constant velocity loading.
Zhang Jianjun, Wang Zhihua, Zhao Longmao
doaj +1 more source

