Results 71 to 80 of about 1,388,210 (307)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Experimental study on dynamic strength and crack evolution of rocks under different strain rates

Meikuang Anquan
The study on the dynamic mechanical characteristics of rocks under impact loading holds significant theoretical guiding significance for achieving controlled blasting during roof cutting blasting.
Tao PAN, Xiao LIU
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Impact loaded structures

, 2004
An experimental apparatus has been constructed to simulate the impact of an aircraft against a nuclear power plant. In order to test the equipment some preliminary tests were carried out with simple inexpensive missiles against a rigid steel plate target.
Kärnä, Tuomo, Saarenheimo, Arja, Tuomala, Markku   +3 more
  +5 more sources

Improvement of the Impact Properties of Composite Laminates by Means of Nano-Modification of the Matrix—A Review

Applied Sciences, 2018
This paper reviews recent works on the application of nanofibers and nanoparticle reinforcements to enhance the interlaminar fracture toughness, to reduce the impact induced damage and to improve the compression after impact performance of fiber ...
Hamed Saghafi, Mohamad Fotouhi, Giangiacomo Minak   +2 more
doaj   +1 more source

Effects of different footwear on landing forces from a grand jeté in trained dancers [PDF]

, 2009
The Grand Jete movement is a popular leap elevation movement used in ballet, modern, contemporary and jazz dance. The move involves taking off from one foot and landing on the other foot reaching the highest point possible in the air and lifting legs to ...
Hanley, B, Miller, S
core  

Sandwich composites impact and indentation behaviour study [PDF]

, 2013
In order to better exploit the natural cork available in Algeria, an experimental characterisation of a jute/epoxy–cork sandwich material to impact and indentation was undertaken.
Bezzazi, Boudjema, Bouvet, Christophe, Hachemane, Belkacem, Zitoune, Redouane   +3 more
core   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Study on dynamic response of cushion layer-reinforced concrete slab under rockfall impact based on smoothed particle hydrodynamics and finite-element method coupling

Reviews on Advanced Materials Science
In the rockfall prevention and control project, the reinforced concrete (RC) slab and sand (gravel soil) soil cushion layer are commonly used to form the protection structure, thereby resisting the rockfall impact.
Mei Xuefeng, Wu Jianli, Wang Teng, Wang Ting, Liang Xiaofei, Wang Yanping, Li Bangxiang, Su Tian, Xu Lina   +8 more
doaj   +1 more source

Fragmentation Processes During Strombolian Explosions Revealed Using Particle Size Distribution Mapping

Frontiers in Earth Science, 2020
Fragmentation dynamics can be described by the size distribution of the fragments generated during an explosion. We approach the problem of magma fragmentation during a Strombolian explosion using the grain size distribution (GSD) of a ballistically ...
Livia Colo’, Maurizio Ripepe, Lucia Gurioli, Andrew J. L. Harris   +3 more
doaj   +1 more source