Results 151 to 160 of about 1,249,207 (265)

Study on plugging law and plugging removal effect of pre filled screen in natural gas hydrate argillaceous silt reservoir. [PDF]

PLoS One
Shi H, Shi J, Du W, Ning F, Xie W, Zhang R, Yu Y.   +6 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Seeds accelerate germination at beneficial planting depths by sensing the sound of rain. [PDF]

Sci Rep
Makris NC, Navarro C.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Borehole pressure response and rock fracture evolution during pipe-assisted high-pressure gas-impact under true-triaxial stress. [PDF]

Sci Rep
Yan Z, Hu S, Wang Y, Li C, Wang L.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Do technologies distract users? Investigating technology experience vs. user wellbeing. [PDF]

Front Psychol
Siyal AW, Lei R.
europepmc   +1 more source

Observations of avalanche impact pressures

, 1973
Observations were made of impact pressures produced by well developed dry snow avalanches. The equipment is described and preliminary results of two years observations are summarized. There is a strong variation of pressure during the passage of an avalanche. The peak pressure, p, observed several times in one avalanche, can be expressed as p=rho v[ 2]/
openaire   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

High-speed radiography of laser-induced shock wave generation in a mock explosive. [PDF]

Sci Rep
Lorenté H, Mouskeftaras A, Sollier A, Lukic B, Rack A, Uteza O, Jumpertz L.   +6 more
europepmc   +1 more source