Results 171 to 180 of about 25,605,949 (420)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Giant impact on early Ganymede and its subsequent reorientation [PDF]
arXivThe origin and early evolution of the Jovian moon Ganymede, known to have an internal ocean, have garnered considerable interest in the field of origin of satellites and life. Ganymede has an ancient impact structure, called a furrow system. The furrow system is the largest impact structures in the outer solar system and the impact should have ...
arxiv
The impact of immigration on the wage structure : Spain 1995-2002 [PDF]
, 2008 In this paper we estimate the impact of inward migration flows on the Spanish wage structure over the period 1995-2002 by constructing counterfactual wage distributions that provide the wages that would have been observed had individual and job ...
Carrasco, Raquel +2 more
core +1 more source
The impact of environment on the dynamical structure of satellite systems
, 2010 We examine the effects of environment on the dynamical structure of satellite systems based on the Millennium--II Simulation. Satellite halos are defined as sub--halos within the virial radius of a host halo.
A. Faltenbacher +42 more
core +1 more source
The roles and applications of extracellular vesicles in cancer
Molecular Oncology, Volume 19, Issue 5, Page 1287-1290, May 2025.Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
The Impact of Energy Prices on Optimum Machinery Size and the Structure of Agriculture: A Georgia Example [PDF]
, 1976 Wesley N. Musser, Ulysses Marable
openalex +1 more source
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
International Journal of Nanomedicine, 2012 Jinsong Zhang1, Ethan W Taylor2, Xiaochun Wan1, Dungeng Peng31School of Tea and Food Science, Anhui Agricultural University, Anhui, People's Republic of China; 2Department of Nanoscience, Joint School of Nanoscience and Nanoengineering ...
Wan X, Taylor EW, Zhang J, Peng D
doaj
Nonlinear seismic analysis of a reactor structure impact between core components [PDF]
, 1975 The seismic analysis of the FFTF-PIOTA (Fast Flux Test Facility-Postirradiation Open Test Assembly), subjected to a horizontal DBE (Design Base Earthquake) is presented. The PIOTA is the first in a set of open test assemblies to be designed for the FFTF.
Hill, R. G.
core +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source