Results 81 to 90 of about 16,071,507 (300)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Productive Interactions (SIAMPI): A Method for Impact Assessment

This resource informs readers about the SIAMPI framework for impact assessment introduced by Spaapen and Van Drooge (2011), enriched with the experiences of the Evaluating Societal Impact team at EUR using the method in two case studies.
Evaluating Societal Impact
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Proximity Lens on Structural Collaborations: A Method for Impact Assessment

This resource provides a description of ‘proximities’ in impact assessment, building on Boschma (2005) and Knoben & Oerlemans (2006). Proximity dimensions provide a lens to identify and highlight the conditions that enable successful cooperation and ...
Evaluating Societal Impact
core   +1 more source

Impact‐Induced Porosity and Microfracturing at the Chicxulub Impact Structure

Journal of Geophysical Research: Planets, 2019
AbstractPorosity and its distribution in impact craters has an important effect on the petrophysical properties of impactites: seismic wave speeds and reflectivity, rock permeability, strength, and density. These properties are important for the identification of potential craters and the understanding of the process and consequences of cratering.
Rae, Auriol S. P., Collins, Gareth S., Morgan, Joanna V., Salge, Tobias, Christeson, Gail L., Leung, Jody, Lofi, Johanna, Gulick, Sean P. S., Poelchau, Michael, Riller, Ulrich, Gebhardt, Catalina, Grieve, Richard A. F., Osinski, Gordon R., IODP- And ICDP Expedition 364 Scientists   +13 more
openaire   +5 more sources

Fault Slip Reversals Preceded the Intraplate 2021 Earthquake Series in the Vienna Basin (Central Europe)

Geophysical Research Letters
Fault‐slip reversals indicate transient stress changes and may illuminate earthquake preparation processes. Here we present high‐resolution observations of sub‐millimetric creep and slip reversals on the Altaquelle Fault, a Quaternary normal fault in the
I. Baroň, J. Jelének, M. Rowberry, R. Melichar, M. delPuy Papí‐Isaba, R. Schultz, J. Balek, J. Stemberk, Ľ. Sokol, H. Hausmann, L. Plan, G. Winkler, B. Grasemann, R. Bürgmann   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact Strategy Development: Questions Bank and Interview Guide

The tool ‘Impact Strategy Development: Questions Bank and Interview Guide’ consists of (1) a three step interview guide and (2) an Excel file with a questions bank to use and tailor for your interviews or other methods for engaging with your community ...
Evaluating Societal Impact
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Thinking About my Impact and Engagement: A Worksheet

What does making positive societal impact mean to you? How do you map current and potential partners and beneficiaries? How to align your work to their needs? This workshop package offers a brief printable worksheet with accompanying presentation slides,
Evaluating Societal Impact
core   +1 more source