Results 241 to 250 of about 12,955,611 (331)

Impact of government subsidy reforms on primary health care efficiency in rural eastern China: an interrupted time series analysis. [PDF]

BMC Health Serv Res
Pu X, Liu R, Wang Z, Huang T, Wang X, Gu Y.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A modelling assessment of the impact of control measures on highly pathogenic avian influenza transmission in poultry in Great Britain. [PDF]

PLoS Comput Biol
Davis CN, Hill EM, Jewell CP, Rysava K, Thompson RN, Tildesley MJ.   +5 more
europepmc   +1 more source

Comprehensive Cancer Networks in the Netherlands: how do they affect quality and costs of care for colon or pancreatic cancer? A retrospective cohort study. [PDF]

BMJ Open
Vrinzen CEJ, Stadhouders N, Bloemendal HJ, Hayen A, Reitsma J, Ten Hove M, Jeurissen PPT, Merkx MAW, Hermens RPMG.   +8 more
europepmc   +1 more source

Does Temporary Baiting Affect White-Tailed Deer Space Use and Movement? New Insights Leveraging Subhourly Location Data. [PDF]

Ecol Evol
Stewart DG, Beaver JT, Cooksey ML, Grantham C, Pierce BL, Lopez RR, Webb SL.   +6 more
europepmc   +1 more source

Therapeutic Use of Virtual Reality for Patients With Fibromyalgia and Chronic Neck Pain: Randomized Controlled Trial. [PDF]

JMIR Rehabil Assist Technol
Úbeda-D'Ocasar E, Moreno-Crespo Y, Cimadevilla-Fernández-Pola E, Hernández-Lougedo J, Navas-Mosqueda Á, Caballero-Corella M, Mayoral-Gonzalo N, Pedauyé-Rueda B, Fernández-Aceñero MJ, Hervás-Pérez JP, Ojedo-Martín C.   +10 more
europepmc   +1 more source

Impact of the algal monitoring and control program in Qingcaosha Reservoir on trihalomethane levels and associated health risks in the effluent of a drinking-water treatment plant in Shanghai: a decadal analysis. [PDF]

Environ Monit Assess
Ren Y, Shi Y, Wu Z, Wu C, Du A, Jin Y, Han F, Qian H, Sui S.   +8 more
europepmc   +1 more source