Results 121 to 130 of about 896,837 (315)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Bone resorption in incompletely impacted mandibular third molars and acute pericoronitis
, 2009 Minoru Yamaoka, Yusuke Ono, Masahiro Takahashi, Ryosuke Doto, Kouichi Yasuda, Takashi Uematsu, Kiyofumi FurusawaMatsumoto Dental University, School of Dentistry, Shiojiri, Nagano, JapanAbstract: Acute pericoronitis (AP) arises frequently in incompletely ...
Ryosuke Doto +4 more
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Dentistry JournalBackground: Canine impaction complicates treatment and prolongs duration, requiring precise localization. CBCT is the gold standard for diagnosis and assessment. However, it involves high radiation exposure and cost.
Teresa Pinho, João Pedro Carvalho
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 1996 P(論文)Many cases of inverted teeth have been reported. In the most cases they have been impacted in the anterior maxilla or they have erupted in the nasal cavity or maxillary sinus.
24901 +17 more
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Contemporary Pediatric DentistryDelayed diagnosis of tooth eruption disturbances may result in the impaction of permanent teeth. This case report describes the clinical management of an impacted maxillary permanent central incisor in an 8-year-old boy with good general health, skeletal
Gabriela Leite Pedroso +4 more
doaj +1 more source
Bilateral Transverse Mandibular Second Molars: A Case Report
Dentistry Journal, 2016 Impaction of mandibular second permanent molars is a rare occurrence, with prevalence rates reported to be between 0.65% and 2.0%. In the absence of systemic conditions, impactions are usually unilateral.
James Puryer +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Saudi Journal of Oral SciencesIntroduction: Assessment of difficulty of surgical transalveolar extraction of impacted mandibular third molar (IMTM) is central in the preoperative planning of the procedure.
Bruno Oludare Ile-Ogedengbe +4 more
doaj +1 more source