Results 151 to 160 of about 896,837 (315)
, 2020 INTRODUCTION: The incidence of impacted wisdom teeth is high, with some 72% of Swedish people aged 20 to 30 years having at least one impacted third molar. Impacted wisdom teeth occur because of a lack of space, obstruction, or abnormal position, and can
Thomas B Dodson, Srinivas M Susarla
core
Impacted maxillary canine: Assessment of prevalence, severity and location of root resorption on maxillary incisors: A retrospective CBCT study. [PDF]
BACKGROUND The maxillary permanent canine is one of the most frequently impacted teeth, which often requires multidisciplinary management. A common complication of canine impaction is root resorption of the adjacent dentition.
Seehra, Jadbinder +4 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Histopathological evaluation of dental follicles associated with impacted third molars
histologically evaluate dental follicles of impacted third molars with no radiographic evidence of pathology. Methods: We carried out both a quantitative and qualitative analysis of pericoronal follicles removed from impacted third molars and ...
Rogério Vera Cruz Ferro Marques, Daniele Meira Conde Marques, Fernanda Ferreira Lopes, Leonardo Victor Galvão-Moreira, Maria Carmen Fontoura Nogueira da Cruz
core
Children impacted by problem drinking.
, 2018 The burden of alcohol harm is often experienced by those around the drinker, such as a family member, friend, co-worker or innocent bystander. Alcohol’s harm to others undermines public safety and is experienced in every community, ranging from the ...
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source