Results 231 to 240 of about 2,037,826 (341)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Successful Treatment with a 6.3-Fr Disposable Digital Flexible Ureteroscope and Holmium Laser Lithotripsy in a 50-Year-Old Man with Large Bilateral Ureteral Stones and Hydronephrosis. [PDF]

Am J Case Rep
Xu X, Mao K, Xu F, Zhong W, Zhao W, Zhang M, Lu Z, Wei G.   +7 more
europepmc   +1 more source

Monitoring hurricane impacted mangrove using remote sensing [PDF]

, 2012
Bégué, Agnès, Claden, M., De Gaulejac, B., Guiral, Daniel, Imbert, Daniel, Laune, P.   +5 more
core  

Damage Mechanism and Modeling of CFRP Laminates Impacted by Single Waterjets: Effect of the Impact Direction

Naidan Hou, Yulong Li, Ping Liu
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Complex odontoma associated with an impacted upper central incisor: a case report and review of literature. [PDF]

J Med Case Rep
Alim N, Akhter F, Elhaddad S, Alasadi A, Alabudulwahab MN.   +4 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Model based noise correction enhances the accuracy of pancreatic CT perfusion blood flow measurements. [PDF]

Sci Rep
Vats N, Mayer P, Kortes F, Klauß M, Grenacher L, Kauczor HU, Stiller W, Skornitzke S.   +7 more
europepmc   +1 more source

Space Syntax Analysis of Spatial Segregation Impacted by Tramway Route Developments in the Eastern Part of Setif city, Algeria [PDF]

Leila Rahmani Kelkoul, Wiem Zerouati, Abdelmalek Farouk Tedjari   +2 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source