Evaluation of nasal passage and palatal morphology in patients with impacted maxillary canine: a retrospective study using cone-beam computed tomography. [PDF]
Hasoğlan ŞT +3 more
europepmc +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Atypical Location of a Complex Odontoma in an 11-Year-Old Girl: A Case Report With a 2-Year Follow-Up. [PDF]
Zalane M +5 more
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Quantifying the potential impact of the cane toad (Rhinella marina) on biodiversity in Australia's Pilbara region. [PDF]
Dunlop J +10 more
europepmc +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Key factors in mandibular third molar surgery: a comprehensive view of their prevalence and interrelationships. [PDF]
Sorooshzadeh M +3 more
europepmc +1 more source
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Patterns of Mandibular Third Molar Impactions and Its Association with Carious Lesions and Periodontal Defects: A Retrospective Cross-Sectional Study. [PDF]
Alsharif SB, Alsharif MB.
europepmc +1 more source

